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澳大利亚墨尔本一家性健康服务机构对生殖道淋病检测呈阳性的无症状和有症状女性的临床表现。

Clinical presentation of asymptomatic and symptomatic women who tested positive for genital gonorrhoea at a sexual health service in Melbourne, Australia.

机构信息

Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC, Australia.

Preventive Medicine and Public Health Training Unit PSMar-UPF-ASPB, Barcelona, Spain.

出版信息

Epidemiol Infect. 2020 Sep 28;148:e240. doi: 10.1017/S0950268820002265.

DOI:10.1017/S0950268820002265
PMID:32985394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7584007/
Abstract

Gonorrhoea cases in women have been rising in Australia in the 2010s but the cause of the increase is not well understood. This cross-sectional study aimed to describe the characteristics of genital gonorrhoea infection in women attending the Melbourne Sexual Health Centre, Australia. Gonorrhoea cases were diagnosed by nucleic acid amplification test (NAAT) and/or culture. Genitourinary specimens were obtained in 12 869 clinic visits in women aged 16 years or above between August 2017 and August 2018. Genital gonorrhoea was detected in 142 (1.1%) of the visits. Almost half of the cases were asymptomatic, 47.9% [95% confidence interval (CI) 39.8-56.1%]; yellow, green or pus-like vaginal discharge was present in 11.3% (95% CI 7.0-17.6%) and other genital symptoms in 40.8% (95% CI 33.1-49.1%) of the cases. The mean time between last sexual contact and onset of symptoms was 7.3 days and between the onset of symptoms to presentation to the clinic was 12.1 days. Half of the cases of genital gonorrhoea among women are asymptomatic and these cases would have been missed by testing of only symptomatic women. Further epidemiological and behavioural research is required to understand the temporal changes in sexual practices among women in Australia.

摘要

澳大利亚 21 世纪 10 年代以来,女性淋病病例有所增加,但病因尚不清楚。本横断面研究旨在描述澳大利亚墨尔本性健康中心就诊女性生殖器淋病感染的特征。淋病病例通过核酸扩增试验(NAAT)和/或培养诊断。2017 年 8 月至 2018 年 8 月期间,在 16 岁及以上的 12869 次就诊中采集了泌尿生殖道标本。在 142 次就诊中检测到生殖器淋病(1.1%)。近一半的病例无症状,占 47.9%(95%可信区间 39.8-56.1%);11.3%(95%可信区间 7.0-17.6%)存在黄色、绿色或脓样阴道分泌物,40.8%(95%可信区间 33.1-49.1%)存在其他生殖器症状。上次性接触到症状出现的平均时间为 7.3 天,从症状出现到就诊的平均时间为 12.1 天。女性生殖器淋病的一半病例无症状,如果仅对有症状的女性进行检测,这些病例可能会被遗漏。需要进一步进行流行病学和行为研究,以了解澳大利亚女性性行为随时间的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04b/7584007/795d5cdd5d14/S0950268820002265_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04b/7584007/795d5cdd5d14/S0950268820002265_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c04b/7584007/795d5cdd5d14/S0950268820002265_fig1.jpg

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