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交通噪音与心血管风险。卡菲利研究,第一阶段。室外噪音水平及风险因素。

Traffic noise and cardiovascular risk. The Caerphilly study, first phase. Outdoor noise levels and risk factors.

作者信息

Babisch W, Gallacher J E, Elwood P C, Ising H

机构信息

Institute for Water, Soil, and Air Hygiene of the Federal Health Office Corrensplatz, Berlin.

出版信息

Arch Environ Health. 1988 Nov-Dec;43(6):407-14. doi: 10.1080/00039896.1988.9935859.

Abstract

As part of the Caerphilly study, traffic noise exposure and risk for ischemic heart disease (IHD) were studied in a sample of 2,512 men aged 45-59 yr. The traffic noise emission level ranged between Leq = 51-70 dB(A) (6-22 hr, 10 min). No association was found between traffic noise and prevalence of IHD. Associations were found between noise and potential IHD risk factors including systolic blood pressure, oestradiol, total cholesterol, plasma viscosity, antithrombin III (increases), cortisol, and platelet count (decrease). Not all results supported the hypothesis that traffic noise increases the risk for IHD. The possibility of confounding cannot be excluded, although an extensive range of potential confounding variables were included in the analysis.

摘要

作为卡菲利研究的一部分,对2512名年龄在45至59岁之间的男性样本进行了交通噪音暴露与缺血性心脏病(IHD)风险的研究。交通噪音排放水平在Leq = 51 - 70 dB(A)之间(6 - 22小时10分钟)。未发现交通噪音与IHD患病率之间存在关联。发现噪音与潜在的IHD风险因素之间存在关联,这些因素包括收缩压、雌二醇、总胆固醇、血浆粘度、抗凝血酶III(升高)、皮质醇和血小板计数(降低)。并非所有结果都支持交通噪音会增加IHD风险这一假设。尽管分析中纳入了广泛的潜在混杂变量,但不能排除混杂的可能性。

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