UMR CNRS 6249 Chrono Environnement, Université de Bourgogne Franche Comté, Dijon Cedex, France.
uMETh, Inserm CIC 1431, CHU de Besançon, 25030, Besancon Cedex, France.
Sci Rep. 2022 Feb 24;12(1):3151. doi: 10.1038/s41598-022-06825-0.
There is growing evidence that environmental noise exposure could increase the risk of atherothrombotic events, including acute myocardial infarction (MI). We analysed the burden of environmental noise on atherothrombotic risk in MI patients. From the RICO survey, 879 consecutive MI patients included from 2004 to 2008 and living in an urban unit of > 237,000 inhabitants were analysed. Atherothrombotic risk was calculated using the TRS-2P score. TRS-2P categories were split into low (TRS-2P = 0/1) (40.8%), medium-low (TRS-2P = 2) (25.7%), medium-high (TRS-2P = 3) (21.8%) and high risk (TRS-2P ≥ 4) (11.6%). Noise exposure was associated with atherothrombotic risk, with the L (OR (95% CI): 1.165 (1.026-1.324)) and L (OR (95CI): 1.157 (1.031-1.298)), for each 10 dB(A) increase. After adjustment, noise exposure remained a predictor of atherothrombotic risk, with L (OR (95% CI): 1.162 (1.011-1.337)) and with L (OR (95% CI): 1.159 (1.019-1.317)). The relationship with transportation L was significant for men (OR (95% CI): 1.260 (1.078-1.472)) but not for women (OR (95% CI): 0.959 (0.763-1.205)). We found a significant association between residential traffic noise exposure and atherothrombotic risk in men but not in women. These results could have major consequences for secondary prevention.
越来越多的证据表明，环境噪声暴露可能会增加动脉血栓形成事件的风险，包括急性心肌梗死（MI）。我们分析了环境噪声对 MI 患者动脉血栓形成风险的影响。该研究分析了 2004 年至 2008 年间居住在城市单位（> 237000 居民）中的 879 名连续 MI 患者。使用 TRS-2P 评分计算动脉血栓形成风险。TRS-2P 类别分为低危（TRS-2P=0/1）（40.8%）、中低危（TRS-2P=2）（25.7%）、中高危（TRS-2P=3）（21.8%）和高危（TRS-2P≥4）（11.6%）。噪声暴露与动脉血栓形成风险相关，每增加 10dB(A)，L（OR（95%CI）：1.165（1.026-1.324））和 L（OR（95CI）：1.157（1.031-1.298））。调整后，噪声暴露仍然是动脉血栓形成风险的预测因子，L（OR（95%CI）：1.162（1.011-1.337））和 L（OR（95%CI）：1.159（1.019-1.317））。交通噪声暴露与男性的关系显著（OR（95%CI）：1.260（1.078-1.472）），但与女性的关系不显著（OR（95%CI）：0.959（0.763-1.205））。我们发现，居住交通噪声暴露与男性的动脉血栓形成风险之间存在显著关联，但在女性中则没有。这些结果可能对二级预防产生重大影响。
