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COVID-19 大流行:维持最佳锌平衡能否增强宿主抵抗力?

COVID-19 Pandemic: Can Maintaining Optimal Zinc Balance Enhance Host Resistance?

机构信息

Department of Pathology, Lake Erie College of Osteopathic Medicine.

Global Affairs Program, McCormack Graduate School of Policy and Global Studies, University of Massachusetts Boston (UMB).

出版信息

Tohoku J Exp Med. 2020 Jul;251(3):175-181. doi: 10.1620/tjem.251.175.

Abstract

The novel coronavirus disease 2019 (COVID-19) is now officially declared as a pandemic by the World Health Organization (WHO), and most parts of the world are taking drastic measures to restrict human movements to contain the infection. Millions around the world are wondering, if there is anything that could be done, other than maintaining high personal hygiene, and be vigilant of the symptoms, to reduce the spread of the disease and chances of getting infected, or at least to lessen the burden of the disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The National and International health agencies, including the National Institutes of Health (NIH), the Centers for Disease Control and Prevention (CDC), and the WHO have provided clear guidelines for both preventive and treatment suggestions. In this article, I will briefly discuss, why keeping adequate zinc balance might enhance the host response and be protective of viral infections.

摘要

新型冠状病毒病 2019(COVID-19)现已被世界卫生组织(WHO)正式宣布为大流行,世界上大多数地区正在采取严厉措施限制人员流动以遏制感染。世界各地数百万人想知道,除了保持高度的个人卫生和警惕症状外,是否还有其他方法可以减少疾病的传播和感染的机会,或者至少减轻由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的疾病负担。包括美国国立卫生研究院(NIH)、美国疾病控制与预防中心(CDC)和世界卫生组织在内的国家和国际卫生机构为预防和治疗建议提供了明确的指导方针。在本文中,我将简要讨论为什么保持足够的锌平衡可能增强宿主反应并对病毒感染具有保护作用。

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