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Hydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial.

作者信息

Guan Wei-Jie, Wei Chun-Hua, Chen Ai-Lan, Sun Xiao-Cong, Guo Guang-Yun, Zou Xu, Shi Jin-Dong, Lai Pei-Zhen, Zheng Ze-Guang, Zhong Nan-Shan

机构信息

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, China.

Department of Respiratory Medicine, Weifang Wei'en Hospital, Weifang, China.

出版信息

J Thorac Dis. 2020 Jun;12(6):3448-3452. doi: 10.21037/jtd-2020-057.

DOI:10.21037/jtd-2020-057
PMID:32642277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7330772/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23cf/7330772/7fa158f90eca/jtd-12-06-3448-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23cf/7330772/7fa158f90eca/jtd-12-06-3448-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23cf/7330772/7fa158f90eca/jtd-12-06-3448-f1.jpg

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Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.中国武汉 2019 年冠状病毒病肺炎患者急性呼吸窘迫综合征和死亡的相关危险因素。
JAMA Intern Med. 2020 Jul 1;180(7):934-943. doi: 10.1001/jamainternmed.2020.0994.
2
Pathological findings of COVID-19 associated with acute respiratory distress syndrome.与急性呼吸窘迫综合征相关的新型冠状病毒肺炎的病理表现
Lancet Respir Med. 2020 Apr;8(4):420-422. doi: 10.1016/S2213-2600(20)30076-X. Epub 2020 Feb 18.
3
Breathing Hydrogen-Oxygen Mixture Decreases Inspiratory Effort in Patients with Tracheal Stenosis.
Biomedicines. 2025 Jan 19;13(1):234. doi: 10.3390/biomedicines13010234.
4
Efficacy of a hydrogen-oxygen generator in treating cigarette smoke-induced chronic obstructive pulmonary disease in rats.氢氧发生器对大鼠香烟烟雾诱导的慢性阻塞性肺疾病的治疗效果。
Curr Res Toxicol. 2024 Dec 28;8:100214. doi: 10.1016/j.crtox.2024.100214. eCollection 2025.
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Additive effect of clove essential oil combined with hydrogen inhalation improves psychological harm caused by lipopolysaccharide in mice.丁香精油联合氢气吸入对脂多糖引起的小鼠心理伤害具有协同作用。
BMC Complement Med Ther. 2024 Nov 15;24(1):399. doi: 10.1186/s12906-024-04682-0.
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Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.用于COVID-19门诊患者的分子氢(Hydro-COVID):一项3期随机、三盲、实用、安慰剂对照、多中心试验。
J Clin Med. 2024 Jul 24;13(15):4308. doi: 10.3390/jcm13154308.
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H inhalation therapy in patients with moderate COVID-19 (HCOVID): a prospective ascending-dose phase I clinical trial.中度 COVID-19 患者的 H 吸入疗法(HCOVID):一项前瞻性递增剂量 I 期临床试验。
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