Gualtieri B, Hertl M
Klinik für Dermatologie und Allergologie, Universitätsklinikum Marburg (UKGM), Baldingerstraße, 35043, Marburg, Deutschland.
Internist (Berl). 2020 Aug;61(8):860-868. doi: 10.1007/s00108-020-00831-y.
Skin diseases represent the second most common paraneoplastic manifestations after endocrine disorders. Paraneoplastic dermatoses may arise as the first clinical sign of occult malignancies, or manifest during the course of a previously diagnosed neoplasm. Dermatoses belonging to the group of obligate paraneoplastic syndromes manifest only in the presence of underlying malignancies. Other skin diseases may be associated with malignancy in a subset of patients.
皮肤疾病是继内分泌紊乱之后第二常见的副肿瘤表现。副肿瘤性皮肤病可能作为隐匿性恶性肿瘤的首个临床症状出现,或在先前诊断的肿瘤病程中显现。属于专性副肿瘤综合征组的皮肤病仅在存在潜在恶性肿瘤时才会出现。其他皮肤疾病可能在一部分患者中与恶性肿瘤相关。