Anderson T E, Woerpel K A
Department of Chemistry, New York University, New York, New York 10003, United States.
Org Lett. 2020 Jul 17;22(14):5690-5694. doi: 10.1021/acs.orglett.0c02075. Epub 2020 Jul 9.
The hydroperoxidation of alkylidenecyclopropanes and other strained alkenes using an -hydroxylamine and molecular oxygen occurred in the absence of catalyst, initiator, or light. The oxidation reaction proceeds through a radical pathway that is initiated by autoxidation of the alkene substrate. The hydroperoxides were converted to their corresponding alcohols and ketones under mild conditions.
使用α-羟胺和分子氧对亚烷基环丙烷及其他张力烯烃进行氢过氧化反应时，无需催化剂、引发剂或光照。氧化反应通过自由基途径进行，该途径由烯烃底物的自动氧化引发。在温和条件下，氢过氧化物可转化为相应的醇和酮。
