Department of Biomedicine, Cancer Metastasis Laboratory, University of Basel and University Hospital Basel, Basel, Switzerland.
SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.
J Exp Med. 2020 Aug 3;217(8). doi: 10.1084/jem.20200356.
Circulating tumor cells are tumor-derived pioneers responsible for the metastatic spread of cancer. Here, we outline recent discoveries, challenges, and future trends for circulating tumor cell investigations, arguing that the time is coming for translation of this work into clinical practice.
循环肿瘤细胞是肿瘤衍生的先驱者，负责癌症的转移扩散。在这里，我们概述了循环肿瘤细胞研究的最新发现、挑战和未来趋势，认为将这项工作转化为临床实践的时机已经到来。
