Mattern W D, Krigman M R, Blythe W B
Clin Nephrol. 1977 Jun;7(6):275-8.
A patient is described who had been on home dialysis for two years before receiving a cadaver kidney transplant. In retrospect, minor speech difficulties were noted two weeks before the transplant. A week after the transplant the characteristic speech, movement and electroencephalographic (EEG) abnormalities of the dialysis encephalopathy syndrome abruptly presented. Relentless neurological deterioration ensued ending in death three months later despite excellent function in the transplant. The significance of this observation is related to current theories of pathogenesis.
描述了一名患者，其在接受尸体肾移植前已进行了两年的家庭透析。回顾发现，移植前两周出现了轻微的言语困难。移植后一周，透析脑病综合征的典型言语、运动和脑电图（EEG）异常突然出现。尽管移植肾功能良好，但随后仍出现了无情的神经功能恶化，三个月后死亡。这一观察结果的意义与当前的发病机制理论有关。
