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透析性脑病中的可溶性脑蛋白

Soluble brain proteins in dialysis encephalopathy.

作者信息

Hindfelt B, Olsson J E

出版信息

Acta Neuropathol. 1980;50(3):241-4. doi: 10.1007/BF00688762.

DOI:10.1007/BF00688762
PMID:7415818
Abstract

Soluble brain proteins were analyzed regionally in a case of dialysis encephalopathy and compared to the findings in patients dying from uncomplicated uremia and acute myocardial infarction. Sixteen individual proteins were quantitated and the results may indicate that dialysis encephalopathy is accompanied by defects in the blood-brain barrier. However, such a postulated does not explain why certain proteins (gamma-trace protein) occur at very low concentrations in dialysis encephalopathy.

摘要

对一例透析性脑病患者的脑可溶性蛋白进行了区域分析,并与死于单纯性尿毒症和急性心肌梗死患者的结果进行了比较。对16种个体蛋白进行了定量分析,结果可能表明透析性脑病伴有血脑屏障缺陷。然而,这样的假设并不能解释为什么某些蛋白(γ-痕量蛋白)在透析性脑病中的浓度非常低。

相似文献

1
Soluble brain proteins in dialysis encephalopathy.透析性脑病中的可溶性脑蛋白
Acta Neuropathol. 1980;50(3):241-4. doi: 10.1007/BF00688762.
2
Brain-aluminium concentration in dialysis encephalopathy.
Lancet. 1978 Apr 29;1(8070):901-4. doi: 10.1016/s0140-6736(78)90681-5.
3
Stress protein inclusions in cerebral vessels in dialysis encephalopathy.透析性脑病中脑血管内的应激蛋白包涵体。
Neuropathol Appl Neurobiol. 1991 Apr;17(2):105-11. doi: 10.1111/j.1365-2990.1991.tb00701.x.
4
Brain gamma-aminobutyric acid deficiency in dialysis encephalopathy.透析性脑病中的脑γ-氨基丁酸缺乏
Neurology. 1985 Feb;35(2):180-4. doi: 10.1212/wnl.35.2.180.
5
Aluminium studies in dialysis encephalopathy.透析性脑病中的铝研究。
Proc Eur Dial Transplant Assoc. 1978;15:157-63.
6
[Development of dialysis encephalopathy in the context of rubidium and aluminum levels in the blood and cerebral cortex of patients with concomitant uremic polyneuropathy on long-term dialysis].
Przegl Lek. 1987;44(3):309-14.
7
The "dialysis encephalopathy syndrome" without dialysis.无透析情况下的“透析性脑病综合征”
Clin Nephrol. 1978 Dec;10(6):250-2.
8
Diazepam and dialysis encephalopathy.地西泮与透析性脑病
Neurology. 1979 Mar;29(3):414-5. doi: 10.1212/wnl.29.3.414.
9
Progressive dialysis encephalopathy ("dialysis dementia").进行性透析性脑病(“透析性痴呆”)
J Neurol. 1980 Jan;222(3):145-57. doi: 10.1007/BF00313113.
10
Dialysis encephalopathy.透析性脑病
Kidney Int Suppl. 1986 Feb;18:S53-7.

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Br Med J. 1978 Apr 8;1(6117):888-90. doi: 10.1136/bmj.1.6117.888.