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乳腺癌是否越来越多地影响年轻女性?

Does Breast Cancer Increasingly Affect Younger Women?

机构信息

Katedra Onkologii, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu (Department of Oncology, Wroclaw Medical University), 53-413 Wrocław, Poland.

Dolnośląskie Centrum Onkologii we Wrocławiu (Wroclaw Comprehensive Cancer Center), 53-413 Wroclaw, Poland.

出版信息

Int J Environ Res Public Health. 2020 Jul 7;17(13):4884. doi: 10.3390/ijerph17134884.

Abstract

Breast cancer is the most frequently diagnosed malignant neoplasm among females. The proportion of women diagnosed in the premenopausal period is relatively small. Nevertheless, this is the most commonly diagnosed cancer among young women. The aim of the study was to analyze the incidence rate of breast cancer in a group of young women based on data obtained in the Lower Silesian Voivodeship between 1984 and 2016. A total of 34,251 women with a diagnosis of invasive breast cancer were analyzed. The median age of diagnosis exhibited an upward trend from 57 to 63. The youngest age of breast cancer diagnosis did not decrease. Women up to the age of 24 were sporadically diagnosed. Given the total number of cases, the proportion of women under the age of 39 was approximately 5%, and it did not increase throughout the entire examination period. The major increase in the growth trend during the analyzed period was observed in a group of women aged of 50-69 (regression coefficient: +24.9) and above 70 (regression coefficient +21.2). In a group of women under 40 the regression coefficient was only +4. It seems that breast cancer does not increasingly affect younger women since the risk in this age group remains low. However, an increasing incidence rate of breast cancer is more commonly observed in premenopausal women.

摘要

乳腺癌是女性中最常见的恶性肿瘤。在绝经前被诊断出患有这种疾病的女性比例相对较小。然而,这是年轻女性中最常见的癌症。本研究的目的是根据 1984 年至 2016 年下西里西亚省的数据,分析一组年轻女性乳腺癌的发病率。共分析了 34251 例浸润性乳腺癌女性患者。诊断时的中位年龄呈上升趋势,从 57 岁上升至 63 岁。诊断出乳腺癌的最小年龄没有下降。24 岁以下的女性偶有被诊断出患有乳腺癌。考虑到总病例数,年龄在 39 岁以下的女性比例约为 5%,且在整个检查期间并未增加。在分析期间,增长趋势的主要增长发生在 50-69 岁(回归系数:+24.9)和 70 岁以上(回归系数:+21.2)的女性群体中。40 岁以下的女性群体的回归系数仅为+4。乳腺癌似乎并没有越来越多地影响年轻女性,因为该年龄段的风险仍然较低。然而,绝经前女性中乳腺癌的发病率上升更为常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/c1a12f9f804e/ijerph-17-04884-g001.jpg

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