• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

乳腺癌是否越来越多地影响年轻女性?

Does Breast Cancer Increasingly Affect Younger Women?

机构信息

Katedra Onkologii, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu (Department of Oncology, Wroclaw Medical University), 53-413 Wrocław, Poland.

Dolnośląskie Centrum Onkologii we Wrocławiu (Wroclaw Comprehensive Cancer Center), 53-413 Wroclaw, Poland.

出版信息

Int J Environ Res Public Health. 2020 Jul 7;17(13):4884. doi: 10.3390/ijerph17134884.

DOI:10.3390/ijerph17134884
PMID:32645841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7370185/
Abstract

Breast cancer is the most frequently diagnosed malignant neoplasm among females. The proportion of women diagnosed in the premenopausal period is relatively small. Nevertheless, this is the most commonly diagnosed cancer among young women. The aim of the study was to analyze the incidence rate of breast cancer in a group of young women based on data obtained in the Lower Silesian Voivodeship between 1984 and 2016. A total of 34,251 women with a diagnosis of invasive breast cancer were analyzed. The median age of diagnosis exhibited an upward trend from 57 to 63. The youngest age of breast cancer diagnosis did not decrease. Women up to the age of 24 were sporadically diagnosed. Given the total number of cases, the proportion of women under the age of 39 was approximately 5%, and it did not increase throughout the entire examination period. The major increase in the growth trend during the analyzed period was observed in a group of women aged of 50-69 (regression coefficient: +24.9) and above 70 (regression coefficient +21.2). In a group of women under 40 the regression coefficient was only +4. It seems that breast cancer does not increasingly affect younger women since the risk in this age group remains low. However, an increasing incidence rate of breast cancer is more commonly observed in premenopausal women.

摘要

乳腺癌是女性中最常见的恶性肿瘤。在绝经前被诊断出患有这种疾病的女性比例相对较小。然而,这是年轻女性中最常见的癌症。本研究的目的是根据 1984 年至 2016 年下西里西亚省的数据,分析一组年轻女性乳腺癌的发病率。共分析了 34251 例浸润性乳腺癌女性患者。诊断时的中位年龄呈上升趋势,从 57 岁上升至 63 岁。诊断出乳腺癌的最小年龄没有下降。24 岁以下的女性偶有被诊断出患有乳腺癌。考虑到总病例数,年龄在 39 岁以下的女性比例约为 5%,且在整个检查期间并未增加。在分析期间,增长趋势的主要增长发生在 50-69 岁(回归系数:+24.9)和 70 岁以上(回归系数:+21.2)的女性群体中。40 岁以下的女性群体的回归系数仅为+4。乳腺癌似乎并没有越来越多地影响年轻女性,因为该年龄段的风险仍然较低。然而,绝经前女性中乳腺癌的发病率上升更为常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/13628860c110/ijerph-17-04884-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/c1a12f9f804e/ijerph-17-04884-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/5eee4af1d75c/ijerph-17-04884-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/13628860c110/ijerph-17-04884-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/c1a12f9f804e/ijerph-17-04884-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/5eee4af1d75c/ijerph-17-04884-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed1/7370185/13628860c110/ijerph-17-04884-g003.jpg

相似文献

1
Does Breast Cancer Increasingly Affect Younger Women?乳腺癌是否越来越多地影响年轻女性?
Int J Environ Res Public Health. 2020 Jul 7;17(13):4884. doi: 10.3390/ijerph17134884.
2
The incidence, age at diagnosis of breast cancer in the Iraqi Kurdish population and comparison to some other countries of Middle-East and West.伊拉克库尔德地区乳腺癌的发病率、发病年龄及与中东和西方国家的比较。
Int J Surg. 2015 Jan;13:71-75. doi: 10.1016/j.ijsu.2014.11.029. Epub 2014 Nov 27.
3
Trends in breast cancer by race and ethnicity: update 2006.不同种族和族裔的乳腺癌发病趋势:2006年更新
CA Cancer J Clin. 2006 May-Jun;56(3):168-83. doi: 10.3322/canjclin.56.3.168.
4
Breast cancer in young women from a low risk population in Nepal.尼泊尔低风险人群中年轻女性的乳腺癌
Asian Pac J Cancer Prev. 2013;14(9):5095-9. doi: 10.7314/apjcp.2013.14.9.5095.
5
Insulin-like growth factor I (IGF-I), IGF-binding proteins, and breast cancer.胰岛素样生长因子I(IGF-I)、IGF结合蛋白与乳腺癌
Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1566-73.
6
Young premenopausal women with breast cancer, especially estrogen receptor negative, are at significantly increased risk for subsequent ovarian cancer.患有乳腺癌的年轻绝经前女性,尤其是雌激素受体阴性者,后续患卵巢癌的风险显著增加。
Discov Med. 2016 Oct;22(121):209-213.
7
A prospective study of breast size and premenopausal breast cancer incidence.一项关于乳房大小与绝经前乳腺癌发病率的前瞻性研究。
Int J Cancer. 2006 Apr 15;118(8):2031-4. doi: 10.1002/ijc.21588.
8
Relationship between age at diagnosis and outcome of premenopausal breast cancer: age less than 35 years is a reasonable cut-off for defining young age-onset breast cancer.诊断时年龄与绝经前乳腺癌预后的关系:年龄<35 岁是定义早发性乳腺癌的合理界限。
Breast Cancer Res Treat. 2010 Jan;119(1):193-200. doi: 10.1007/s10549-009-0388-z. Epub 2009 Apr 7.
9
Breast cancer age at diagnosis patterns in four Latin American Populations: A comparison with North American countries.四个拉丁美洲人群乳腺癌诊断年龄模式:与北美国家的比较。
Cancer Epidemiol. 2015 Dec;39(6):831-7. doi: 10.1016/j.canep.2015.10.004. Epub 2015 Oct 24.
10
Body fatness throughout the life course and the incidence of premenopausal breast cancer.一生中的体脂与绝经前乳腺癌的发病率
Int J Epidemiol. 2016 Aug;45(4):1103-1112. doi: 10.1093/ije/dyw149. Epub 2016 Jul 27.

引用本文的文献

1
Trends in disease characteristics and premature mortality among hospitalised middle-aged patients in Anhui Southern Area, China, between 2011 and 2020: a cross-sectional study.2011年至2020年中国安徽南部地区住院中年患者的疾病特征和过早死亡率趋势:一项横断面研究。
BMJ Open. 2024 Dec 10;14(12):e085978. doi: 10.1136/bmjopen-2024-085978.
2
Global epidemiology of breast cancer based on risk factors: a systematic review.基于风险因素的全球乳腺癌流行病学:一项系统综述。
Front Oncol. 2023 Oct 10;13:1240098. doi: 10.3389/fonc.2023.1240098. eCollection 2023.
3
Second breast cancer: recurrence score results, clinicopathologic characteristics, adjuvant treatments, and outcomes-exploratory analysis of the Clalit registry.

本文引用的文献

1
ESO-ESMO 4th International Consensus Guidelines for Breast Cancer in Young Women (BCY4).ESO-ESMO 4 版年轻女性乳腺癌国际共识指南(BCY4)。
Ann Oncol. 2020 Jun;31(6):674-696. doi: 10.1016/j.annonc.2020.03.284. Epub 2020 Mar 19.
2
Cancer statistics, 2020.癌症统计数据,2020 年。
CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.
3
Age-standardized cancer-incidence trends in Canada, 1971-2015.加拿大 1971-2015 年标准化癌症发病率趋势。
第二原发性乳腺癌:复发评分结果、临床病理特征、辅助治疗及结局——克拉利特登记处的探索性分析
NPJ Breast Cancer. 2023 Sep 30;9(1):79. doi: 10.1038/s41523-023-00586-3.
4
Metabolic Reprogramming by Ribitol Expands the Therapeutic Window of BETi JQ1 against Breast Cancer.核糖醇介导的代谢重编程拓宽了BETi JQ1治疗乳腺癌的治疗窗口。
Cancers (Basel). 2023 Sep 1;15(17):4356. doi: 10.3390/cancers15174356.
5
Dynamic contrast-enhanced magnetic resonance imaging features and apparent diffusion coefficient value of HER2-positive/HR-negative breast carcinoma.人表皮生长因子受体2阳性/激素受体阴性乳腺癌的动态对比增强磁共振成像特征及表观扩散系数值
Quant Imaging Med Surg. 2023 Aug 1;13(8):4816-4825. doi: 10.21037/qims-22-1318. Epub 2023 May 12.
6
Expression and Clinical Significance of in Primary Breast Cancer.原发性乳腺癌中 的表达及临床意义。 (原文中“of”后面缺少具体内容)
Int J Gen Med. 2023 Jun 12;16:2405-2417. doi: 10.2147/IJGM.S407725. eCollection 2023.
7
Metabolomics of Breast Cancer: A Review.乳腺癌的代谢组学:综述
Metabolites. 2022 Jul 13;12(7):643. doi: 10.3390/metabo12070643.
8
Clinical features and prognostic factors of breast cancer in young women: a retrospective single-center study.年轻女性乳腺癌的临床特征及预后因素:一项回顾性单中心研究
Arch Gynecol Obstet. 2023 Mar;307(3):957-968. doi: 10.1007/s00404-022-06670-6. Epub 2022 Jul 15.
9
Downregulated Copper Homeostasis-Related Gene FOXO1 as a Novel Indicator for the Prognosis and Immune Response of Breast Cancer.下调的铜稳态相关基因 FOXO1 作为乳腺癌预后和免疫反应的新型标志物。
J Immunol Res. 2022 Jun 28;2022:9140461. doi: 10.1155/2022/9140461. eCollection 2022.
10
Digital phenotyping in young breast cancer patients treated with neoadjuvant chemotherapy (the NeoFit Trial): protocol for a national, multicenter single-arm trial.数字表型分析在接受新辅助化疗的年轻乳腺癌患者中的应用(NeoFit 试验):一项全国性、多中心单臂试验的方案。
BMC Cancer. 2022 May 4;22(1):493. doi: 10.1186/s12885-022-09608-y.
CMAJ. 2019 Nov 18;191(46):E1262-E1273. doi: 10.1503/cmaj.190355.
4
Breast cancer statistics, 2019.乳腺癌统计数据,2019 年。
CA Cancer J Clin. 2019 Nov;69(6):438-451. doi: 10.3322/caac.21583. Epub 2019 Oct 2.
5
Fertility concerns, preservation strategies and quality of life in young women with breast cancer: Baseline results from an ongoing prospective cohort study in selected European Centers.生育问题、保留策略和年轻乳腺癌女性的生活质量:在选定的欧洲中心进行的一项正在进行的前瞻性队列研究的基线结果。
Breast. 2019 Oct;47:85-92. doi: 10.1016/j.breast.2019.07.001. Epub 2019 Jul 10.
6
Annual Report to the Nation on the Status of Cancer, Featuring Cancer in Men and Women Age 20-49 Years.《国家癌症报告:20-49 岁男性和女性癌症现状》
J Natl Cancer Inst. 2019 Dec 1;111(12):1279-1297. doi: 10.1093/jnci/djz106.
7
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.全球癌症统计数据 2018:GLOBOCAN 对全球 185 个国家/地区 36 种癌症的发病率和死亡率的估计。
CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
8
Trends in breast cancer mortality by stage at diagnosis among young women in the United States.美国年轻女性诊断时乳腺癌分期死亡率趋势。
Cancer. 2018 Sep 1;124(17):3500-3509. doi: 10.1002/cncr.31638. Epub 2018 Sep 6.
9
Proportion of U.S. Trends in Breast Cancer Incidence Attributable to Long-term Changes in Risk Factor Distributions.美国乳腺癌发病率趋势中归因于风险因素分布长期变化的比例。
Cancer Epidemiol Biomarkers Prev. 2018 Oct;27(10):1214-1222. doi: 10.1158/1055-9965.EPI-18-0098. Epub 2018 Aug 1.
10
Trends in incidence, mortality and survival in women with breast cancer from 1985 to 2012 in Granada, Spain: a population-based study.1985 年至 2012 年西班牙格拉纳达女性乳腺癌发病率、死亡率和生存率趋势:一项基于人群的研究。
BMC Cancer. 2018 Aug 2;18(1):781. doi: 10.1186/s12885-018-4682-1.