Subramani Ramadevi, Poudel Seeta, Smith Kenneth D, Estrada Adriana, Lakshmanaswamy Rajkumar
Center of Emphasis in Cancer, Department of Molecular and Translation Medicine, Paul L. Foster School of Medicine, Texas Tech Health Science Center El Paso, El Paso, TX 79905, USA.
L. Frederick Francis Graduate School of Biomedical Sciences, Texas Tech Health Science Center El Paso, El Paso, TX 79905, USA.
Metabolites. 2022 Jul 13;12(7):643. doi: 10.3390/metabo12070643.
Breast cancer is the most commonly diagnosed cancer in women worldwide. Major advances have been made towards breast cancer prevention and treatment. Unfortunately, the incidence of breast cancer is still increasing globally. Metabolomics is the field of science which studies all the metabolites in a cell, tissue, system, or organism. Metabolomics can provide information on dynamic changes occurring during cancer development and progression. The metabolites identified using cutting-edge metabolomics techniques will result in the identification of biomarkers for the early detection, diagnosis, and treatment of cancers. This review briefly introduces the metabolic changes in cancer with particular focus on breast cancer.
乳腺癌是全球女性中最常被诊断出的癌症。在乳腺癌的预防和治疗方面已经取得了重大进展。不幸的是，全球乳腺癌的发病率仍在上升。代谢组学是研究细胞、组织、系统或生物体中所有代谢物的科学领域。代谢组学可以提供有关癌症发生和发展过程中动态变化的信息。使用前沿代谢组学技术鉴定出的代谢物将有助于识别用于癌症早期检测、诊断和治疗的生物标志物。本综述简要介绍了癌症中的代谢变化，尤其侧重于乳腺癌。
