Tramèr Lucas, Mertz Kirsten D, Huegli Rolf, Hinic Vladimira, Jost Lorenz, Burkhalter Felix, Wirz Sebastian, Tarr Philip E
University Department of Medicine, Kantonsspital Baselland, University of Basel, 4101 Bruderholz, Switzerland.
Cantonal Institute of Pathology, 4410 Liestal, Switzerland.
J Clin Med. 2020 Jul 7;9(7):2141. doi: 10.3390/jcm9072141.
Nocardiosis is primarily an opportunistic infection affecting immunosuppressed individuals, in whom it most commonly presents as pulmonary infection and sometimes cerebral abscesses. Isolated abdominal or retroperitoneal nocardiosis is rare. Here, we report the second case, to our knowledge, of isolated abdominal nocardiosis due to and provide a comprehensive review of intra-abdominal nocardiosis. The acquisition of abdominal nocardiosis is believed to occur via hematogenous spreading after pulmonary or percutaneous inoculation or possibly via direct abdominal inoculation. Cases of peritonitis have been reported in patients on peritoneal dialysis. Accurate diagnosis of abdominal nocardiosis requires histological and/or microbiological examination of appropriate, radiologically or surgically obtained biopsy specimens. Malignancy may initially be suspected when the patient presents with an abdominal mass. Successful therapy usually includes either percutaneous or surgical abscess drainage plus prolonged combination antimicrobial therapy.
诺卡菌病主要是一种影响免疫功能低下个体的机会性感染,在这些个体中,它最常表现为肺部感染,有时也表现为脑脓肿。孤立性腹部或腹膜后诺卡菌病很少见。在此,据我们所知,我们报告第二例由[具体病因未给出]引起的孤立性腹部诺卡菌病病例,并对腹腔内诺卡菌病进行全面综述。腹腔诺卡菌病的感染被认为是在肺部或经皮接种后通过血行播散发生的,或者可能是通过直接腹腔接种。已有腹膜透析患者发生腹膜炎的病例报道。腹腔诺卡菌病的准确诊断需要对经放射学或手术获取的适当活检标本进行组织学和/或微生物学检查。当患者出现腹部肿块时,最初可能会怀疑为恶性肿瘤。成功的治疗通常包括经皮或手术脓肿引流以及延长的联合抗菌治疗。