Lee K, Pritchard E, Donahoe S L, Malik R, Krockenberger M
Sydney School of Veterinary Science, The University of Sydney, Sydney, New South Wales, 2006, Australia.
Centre for Veterinary Education, The University of Sydney, Sydney, New South Wales, 2006, Australia.
Aust Vet J. 2025 Jan-Feb;103(1-2):27-32. doi: 10.1111/avj.13383. Epub 2024 Oct 12.
Nocardia infections in cats most commonly present as subcutaneous wounds, or less commonly, as pneumonia, purulent pleurisy and disseminated disease. Abdominal involvement is rarely reported, and to date, localised retroperitoneal infection has only been reported in people. This report describes a five-year-old domestic shorthair cat living in Canberra, Australia, that presented with a two-month history of pyrexia and inappetence progressing to anorexia. Ultrasonography showed a large retroperitoneal mass incorporating both ureters. Euthanasia was elected because of the guarded prognosis. Necropsy examination revealed the mass to be comprised of extensive pyogranulomatous inflammation with fibrosis, Splendore-Hoeppli phenomenon and filamentous Gram-positive bacteria. Culture and MALDI-TOF mass spectrometry identified the causative agent as Nocardia brasiliensis. N. brasiliensis is commonly diagnosed as a cause of cutaneous nocardiosis in Australian human patients, but to date has only been reported in one cat from the United States and one dog from Australia. A treatment approach that might have been used in such a case is provided even though the cat's owners elected not to proceed with surgical intervention.
猫的诺卡菌感染最常见表现为皮下伤口，较少见的表现为肺炎、化脓性胸膜炎和播散性疾病。腹部受累情况鲜有报道，迄今为止，局限性腹膜后感染仅在人类中有过报道。本报告描述了一只生活在澳大利亚堪培拉的5岁家养短毛猫，该猫有两个月的发热和食欲不振病史，进而发展为厌食。超声检查显示一个包含双侧输尿管的巨大腹膜后肿块。由于预后不佳，决定实施安乐死。尸检发现肿块由广泛的脓性肉芽肿性炎症伴纤维化、Splendore-Hoeppli现象和丝状革兰氏阳性菌组成。培养和基质辅助激光解吸电离飞行时间质谱鉴定病原体为巴西诺卡菌。巴西诺卡菌通常被诊断为澳大利亚人类患者皮肤诺卡菌病的病因，但迄今为止仅在美国的一只猫和澳大利亚的一只狗中有过报道。尽管猫主人选择不进行手术干预，但本文提供了针对此类病例可能采用的治疗方法。
