构建纳米颗粒-生物大分子界面
Engineering the nanoparticle-biomacromolecule interface.
作者信息
You Chang-Cheng, Verma Ayush, Rotello Vincent M
机构信息
Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
出版信息
Soft Matter. 2006 Feb 15;2(3):190-204. doi: 10.1039/b517354j.
Monolayer-protected nanoparticles feature tunable size, surface functionality and core material, providing scaffolds for targeting biomacromolecules. This review highlights recent advances in nanoparticle-biomacromolecule interactions, focusing on two key areas: (1) The modulation of structure and function of biomacromolecules through engineered interactions with nanoparticle surfaces; (2) The use of biomacromolecules as building blocks for nanostructured materials.
单层保护纳米粒子具有可调节的尺寸、表面功能和核心材料，为靶向生物大分子提供了支架。本综述重点介绍了纳米粒子与生物大分子相互作用的最新进展，聚焦于两个关键领域：（1）通过与纳米粒子表面的工程相互作用来调节生物大分子的结构和功能；（2）将生物大分子用作纳米结构材料的构建单元。
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