School of Computer Science, Hubei University of Technology, Wuhan, Hubei, China.
Wollongong Joint Institute, Central China Normal University, Wuhan, Hubei, China.
BMC Med Inform Decis Mak. 2020 Jul 9;20(Suppl 3):138. doi: 10.1186/s12911-020-1121-4.
Evidence-based Clinical Decision Support Systems (CDSSs) usually obtain clinical evidences from randomized controlled trials based on coarse-grained groups. Individuals who are beyond the scope of the original trials cannot be accurately and objectively supported. Also, patients' opinions and preferences towards the health care delivered to them have rarely been considered. In this regards, we propose to use clinical experience data as an evidence to support patient-oriented decision-making.
The experience data of similar patients from social networks as subjective evidence and the argumentation rules derived from clinical guidelines as objective evidence are combined to support decision making together. They are integrated into a comprehensive decision support architecture. The patient reviews are crawled from social networks and sentimentally analyzed to become structured data which are mapped to the Clinical Sentiment Ontology (CSO). This is used to build a Patient Experience Knowledge Base (PEKB) that can complement the original clinical guidelines. An Experience Inference Engine (EIE) is developed to match similar experience cases from both patient preference features and patient conditions and ultimately, comprehensive clinical recommendations are generated.
A prototype system is designed and implemented to show the feasibility of the decision support architecture. The system allows patients and domain experts to easily explore various choices and trade-offs via modifying attribute values to select the most appropriate decisions.
The integrated decision support architecture built is generic to solving a wide range of clinical problems. This will lead to better-informed clinical decisions and ultimately improved patient care.
循证临床决策支持系统(CDSS)通常基于粗粒度组从随机对照试验中获取临床证据。超出原始试验范围的个体无法得到准确和客观的支持。此外,患者对所接受的医疗保健的意见和偏好很少被考虑。在这方面,我们建议使用临床经验数据作为证据来支持以患者为中心的决策。
将社交网络中类似患者的经验数据作为主观证据,以及从临床指南中推导出的论证规则作为客观证据结合起来共同支持决策。它们被整合到一个综合的决策支持架构中。患者评论从社交网络中抓取并进行情感分析,转化为结构化数据,并映射到临床情感本体(CSO)中。这用于构建一个可以补充原始临床指南的患者体验知识库(PEKB)。开发了一个经验推理引擎(EIE),用于从患者偏好特征和患者状况两方面匹配类似的经验案例,并最终生成全面的临床建议。
设计并实现了一个原型系统,以展示决策支持架构的可行性。系统允许患者和领域专家通过修改属性值轻松探索各种选择和权衡,以选择最合适的决策。
所构建的综合决策支持架构具有通用性,可以解决广泛的临床问题。这将导致更明智的临床决策,并最终改善患者护理。