Bagger-Sjöbäck D, Takumida M
Department of Otolaryngology, Karolinska Sjukhuset, Stockholm, Sweden.
Acta Otolaryngol. 1988 Nov-Dec;106(5-6):393-403. doi: 10.3109/00016488809122262.
The stereometrical arrangement of the sensory hair bundles in vestibular epithelia of the guinea pig was studied with high-resolution scanning electronmicroscopy. Besides the previously known arrangement in tall and short hair bundles, a new morphological criterion dividing the hair bundles into two separate populations is described. Thus the hair bundles can be separated into a loose and a tight type, depending on the interrelationship between the individual stereocilia. The cilia in the loose hair bundle are arranged in longitudinal rows parallel with the cell's plane of polarization, so that the stereocilia increasing stepwise in height are compressed tightly together. The stereocilia in the tight hair bundle type are arranged in equally tall transverse rows in which the cilia are situated directly adjacent to each other. While all the stereocilia are connected by thin filaments along the entire course of their shafts, their bevelled tips are connected by a single tip link to the shaft of the adjacent, taller stereocilium. The tip link morphology differs between the two hair bundle types. It is assumed that these two different types of hair bundles have different mechanical properties, which could indicate a higher degree of selectivity on the hair cell level in the vestibular end organs.
利用高分辨率扫描电子显微镜研究了豚鼠前庭上皮中感觉毛束的立体排列。除了先前已知的高毛束和矮毛束排列方式外，还描述了一种将毛束分为两个独立群体的新形态学标准。因此，根据单个静纤毛之间的相互关系，毛束可分为松散型和紧密型。松散毛束中的纤毛沿与细胞极化平面平行的纵向排列，因此高度逐步增加的静纤毛紧密地挤压在一起。紧密毛束型中的静纤毛排列成等高的横向排，其中纤毛彼此直接相邻。虽然所有静纤毛在其整个轴的长度上都由细丝连接，但它们的斜切尖端通过单个顶端连接与相邻较高静纤毛的轴相连。两种毛束类型的顶端连接形态不同。据推测，这两种不同类型的毛束具有不同的机械特性，这可能表明前庭终器中毛细胞水平上具有更高的选择性。
