Wang Jian, Shen Huiliang
Department of Dermatology, Zhejiang Province Dermatology Hospital, Huzhou City, Zhejiang Province, 313200, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Aug 9;16:2129-2133. doi: 10.2147/CCID.S421534. eCollection 2023.
Wolf's isotopic response (WIR) refers to the appearance of a new skin disorder at the exact site of an unrelated skin disorder that had previously been cured. The most common primary skin disease in which WIR occurs is herpes zoster. Despite numerous theories being put forward to explain this occurrence, including viral, vascular, immunological, and neurological hypotheses, the pathogenesis of WIR after herpes zoster remains unclear. We report the case of a 76-year-old patient who presented with keloids at the site of the original herpes zoster. Based on this observation and a review of the literature, The clinical characteristics and possible theoretical reasons for keloids after herpes zoster will be discussed.
沃尔夫同位素反应（WIR）是指在先前已治愈的无关皮肤病的确切部位出现一种新的皮肤病。发生WIR最常见的原发性皮肤病是带状疱疹。尽管提出了许多理论来解释这种现象，包括病毒、血管、免疫和神经假说，但带状疱疹后WIR的发病机制仍不清楚。我们报告了一例76岁患者，其在原带状疱疹部位出现瘢痕疙瘩。基于这一观察结果并结合文献复习，将讨论带状疱疹后瘢痕疙瘩的临床特征及可能的理论原因。
