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上腔静脉血栓形成和扩张型心肌病作为白塞病的初始表现。

Superior vena cava thrombosis and dilated cardiomyopathy as initial presentations of Behcet's disease.

作者信息

Elzanaty Ahmed M, Awad Mohammed T, Acharaya Ashu, Sabbagh Ebrahim, Elsheikh Eman, AbdAlamir Moshrik

机构信息

Internal Medicine Departement, University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614 USA.

Cardiology Departement, University of Toledo, Toledo, Ohio USA.

出版信息

Thromb J. 2020 Jul 6;18:12. doi: 10.1186/s12959-020-00225-y. eCollection 2020.

DOI:10.1186/s12959-020-00225-y
PMID:32647496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7336494/
Abstract

BACKGROUND

Bechet's disease (BD) is a relatively rare disease that causes recurrent oral and genital ulcers in addition to a variety of systemic manifestations. Concomitant superior-vena-cava (SVC) thrombosis and cardiac involvement with dilated cardiomyopathy (DCM) as initial presentations for BD is considered rare.

CASE PRESENTATION

A 32-year-old-man presenting with intractable headaches and dyspnea. He was later diagnosed with SVC thrombosis and DCM. A diagnosis of BD was made after detailed history-taking.

CONCLUSIONS

Cardiovascular manifisations can be the initial presentation of BD. We aim to highlight the importance of early clinical recognition of BD as a cause of DCM and SVC thrombosis.

摘要

背景

白塞病(BD)是一种相对罕见的疾病,除了多种全身表现外,还会导致复发性口腔和生殖器溃疡。白塞病以伴有上腔静脉(SVC)血栓形成和心脏受累合并扩张型心肌病(DCM)为首发表现较为罕见。

病例报告

一名32岁男性,出现顽固性头痛和呼吸困难。随后他被诊断为SVC血栓形成和DCM。经过详细的病史询问后,确诊为白塞病。

结论

心血管表现可能是白塞病的首发症状。我们旨在强调早期临床识别白塞病作为DCM和SVC血栓形成病因的重要性。

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本文引用的文献

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Ultrasound Med Biol. 2018 Apr;44(4):825-830. doi: 10.1016/j.ultrasmedbio.2017.12.010. Epub 2018 Jan 17.
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Intracardiac thrombus in patients with Behcet's disease: clinical correlates, imaging features, and outcome: a retrospective, single-center experience.白塞病患者的心内血栓:临床关联、影像学特征及预后:一项回顾性单中心研究
Clin Rheumatol. 2016 Oct;35(10):2501-7. doi: 10.1007/s10067-015-3161-1. Epub 2016 Jan 11.
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A giant left ventricular pseudoaneurysm in Behçet's disease: a case report.
白塞病合并巨大左心室假性动脉瘤:一例报告
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Major vessel thrombosis in Behçet's disease: the dilemma of anticoagulant therapy - the approach of rheumatologists from different countries.白塞病中的大血管血栓形成:抗凝治疗的困境——不同国家风湿病学家的处理方法。
Clin Exp Rheumatol. 2012 Sep-Oct;30(5):735-40. Epub 2012 Oct 17.
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Spectrum of cardiac lesions in Behçet disease: a series of 52 patients and review of the literature.白塞病中心脏病变谱:52例患者系列研究及文献综述
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A diagnosis not to be missed: Behcet's disease as a cause of dilated cardiomyopathy in a young Arab male patient.不容忽视的诊断:白塞病导致年轻阿拉伯男性扩张型心肌病。
Int J Rheum Dis. 2010 Feb 1;13(1):97-9. doi: 10.1111/j.1756-185X.2009.01451.x.
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Behçet's Disease: an Insight from a Cardiologist's Point of View.白塞病:心脏病专家视角的见解
Open Cardiovasc Med J. 2010 Feb 23;4:63-70. doi: 10.2174/1874192401004020063.
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