Liu Nina, Mathews Adithya, Swanson Justin, Mhaskar Rahul, Mathews Akshay, Ayoubi Noura, Mirza Abu-Sayeef
Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Department of Internal Medicine, University of South Florida, Tampa, FL, USA.
SAGE Open Med. 2020 Jun 30;8:2050312120938224. doi: 10.1177/2050312120938224. eCollection 2020.
Aspirin is an effective anti-inflammatory and antiplatelet agent as an irreversible inhibitor of cyclooxygenase. In 2016, the U.S. Preventive Services Task Force recommended aspirin for primary prevention of cardiovascular disease in patients aged 50-69 years with a 10% or greater 10-year cardiovascular disease risk. Current guidelines for patients with prior myocardial infarction or coronary artery disease recommend aspirin use for the secondary prevention of cardiovascular disease. Due to the lack of literature describing adherence to these recommendations in the uninsured patient population, we studied aspirin use for cardiovascular disease prevention in free medical clinics.
We conducted a cross sectional study of uninsured patients who visited nine free medical clinics in 2016-2017. Data from the records of 8857 patients were combined into a database for analysis. 10-year Framingham risk scores for coronary artery disease were calculated for the 50-69-year-old population to evaluate which patients qualified for aspirin usage. Aspirin use was assessed for patients with prior myocardial infarction or coronary artery disease.
In total, 1443 patients met the criteria to take aspirin for primary prevention of cardiovascular disease, but just 17% of these patients aged 50-59 years were on the medication. About 15% of the patients aged 60-69 years were taking aspirin. Of the 297 patients who had prior myocardial infarction or coronary artery disease, 50% were taking aspirin for secondary prevention.
Among the uninsured population, there are low rates of aspirin use for risk reduction of cardiovascular disease. This study demonstrates that improvements are needed to increase adherence to current guidelines and address barriers uninsured patients may face in maintaining their cardiovascular health.
阿司匹林作为环氧化酶的不可逆抑制剂,是一种有效的抗炎和抗血小板药物。2016年,美国预防服务工作组建议,对于10年心血管疾病风险为10%或更高的50 - 69岁患者,使用阿司匹林进行心血管疾病的一级预防。目前针对既往有心肌梗死或冠状动脉疾病患者的指南推荐使用阿司匹林进行心血管疾病的二级预防。由于缺乏关于未参保患者群体对这些建议依从性的文献,我们研究了免费医疗诊所中阿司匹林用于预防心血管疾病的情况。
我们对2016 - 2017年访问9家免费医疗诊所的未参保患者进行了横断面研究。将8857例患者记录中的数据合并到一个数据库中进行分析。计算了50 - 69岁人群的10年弗雷明汉冠心病风险评分,以评估哪些患者符合使用阿司匹林的条件。对既往有心肌梗死或冠状动脉疾病的患者的阿司匹林使用情况进行了评估。
总共有1443例患者符合服用阿司匹林进行心血管疾病一级预防的标准,但在这些50 - 59岁的患者中,只有17%的患者正在服用该药物。60 - 69岁的患者中约有15%正在服用阿司匹林。在297例既往有心肌梗死或冠状动脉疾病的患者中,50%正在服用阿司匹林进行二级预防。
在未参保人群中,使用阿司匹林降低心血管疾病风险的比例较低。这项研究表明,需要做出改进,以提高对现行指南的依从性,并解决未参保患者在维护心血管健康方面可能面临的障碍。