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Relapsed/Refractory ETP-ALL Successfully Treated With Venetoclax and Nelarabine as a Bridge to Allogeneic Stem Cell Transplant.

作者信息

McEwan Ashley, Pitiyarachchi Omali, Viiala Nicholas

机构信息

Department of Hematology, Liverpool Hospital, Sydney, Australia.

Chris O'Brien Lifehouse, Department of Medical Oncology, Sydney, Australia.

出版信息

Hemasphere. 2020 Jun 8;4(3):e379. doi: 10.1097/HS9.0000000000000379. eCollection 2020 Jun.

DOI:10.1097/HS9.0000000000000379
PMID:32647798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7306301/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9751/7306301/0537054a6e84/hs9-4-e379-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9751/7306301/0537054a6e84/hs9-4-e379-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9751/7306301/0537054a6e84/hs9-4-e379-g001.jpg

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本文引用的文献

1
Clinical Experience With Venetoclax Combined With Chemotherapy for Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia. Venetoclax 联合化疗治疗复发或难治性 T 细胞急性淋巴细胞白血病的临床经验。
Clin Lymphoma Myeloma Leuk. 2020 Apr;20(4):212-218. doi: 10.1016/j.clml.2019.09.608. Epub 2019 Sep 30.
2
Next-Generation Sequencing in Acute Lymphoblastic Leukemia.急性淋巴细胞白血病中的二代测序。
Int J Mol Sci. 2019 Jun 15;20(12):2929. doi: 10.3390/ijms20122929.
3
First report of clinical response to Venetoclax in Early T-cell Precursor Acute Lymphoblastic Leukemia.
Pegaspargase, venetoclax, and nelarabine: a successful bridge to allogeneic hematopoietic stem cell transplantation in a relapsed/refractory T-cell acute lymphoblastic leukemia patient.
培门冬酶、维奈克拉和奈拉滨:一名复发/难治性T细胞急性淋巴细胞白血病患者成功过渡到异基因造血干细胞移植的桥梁。
Ann Hematol. 2023 Jun;102(6):1599-1600. doi: 10.1007/s00277-023-05231-4. Epub 2023 Apr 26.
4
Therapeutic Targeting of MERTK and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia.MERTK和BCL-2在T细胞和早期T前体急性淋巴细胞白血病中的治疗靶向作用
Cancers (Basel). 2022 Dec 13;14(24):6142. doi: 10.3390/cancers14246142.
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Targeting Leukemia-Initiating Cells and Leukemic Niches: The Next Therapy Station for T-Cell Acute Lymphoblastic Leukemia?靶向白血病起始细胞和白血病微环境:T细胞急性淋巴细胞白血病的下一个治疗靶点?
Cancers (Basel). 2022 Nov 17;14(22):5655. doi: 10.3390/cancers14225655.
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Novel Treatments for Pediatric Relapsed or Refractory Acute B-Cell Lineage Lymphoblastic Leukemia: Precision Medicine Era.小儿复发性或难治性急性B细胞系淋巴细胞白血病的新型治疗方法:精准医学时代
Front Pediatr. 2022 Jun 23;10:923419. doi: 10.3389/fped.2022.923419. eCollection 2022.
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Front Cell Dev Biol. 2022 May 13;10:899752. doi: 10.3389/fcell.2022.899752. eCollection 2022.
8
The New Therapeutic Strategies in Pediatric T-Cell Acute Lymphoblastic Leukemia.小儿 T 细胞急性淋巴细胞白血病的新治疗策略。
Int J Mol Sci. 2021 Apr 26;22(9):4502. doi: 10.3390/ijms22094502.
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JCO Precis Oncol. 2018;2. doi: 10.1200/PO.18.00127. Epub 2018 Aug 22.
4
Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL.缺失增强了 HSC 的自我更新,从而驱动 T-ALL 中的肿瘤起始和白血病干细胞活性。
Cancer Discov. 2019 Mar;9(3):436-451. doi: 10.1158/2159-8290.CD-18-1005. Epub 2018 Dec 19.
5
T cell acute lymphoblastic leukemia (T-ALL): New insights into the cellular origins and infiltration mechanisms common and unique among hematologic malignancies.T 细胞急性淋巴细胞白血病(T-ALL):血液恶性肿瘤中共同和独特的细胞起源和浸润机制的新见解。
Blood Rev. 2018 Jan;32(1):36-51. doi: 10.1016/j.blre.2017.08.006. Epub 2017 Aug 15.
6
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype.青少年及成人早期T细胞前体急性淋巴细胞白血病/淋巴瘤(ETP-ALL/LBL):一种高危亚型
Blood. 2016 Apr 14;127(15):1863-9. doi: 10.1182/blood-2015-08-661702. Epub 2016 Jan 8.
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ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.ABT-199 通过抑制 BCL-2 作为 T 细胞急性淋巴细胞白血病的一种新的治疗策略。
Blood. 2014 Dec 11;124(25):3738-47. doi: 10.1182/blood-2014-05-574566. Epub 2014 Oct 9.
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Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.T细胞急性淋巴细胞白血病的成熟阶段决定了对BCL-2与BCL-XL的依赖性以及对ABT-199的敏感性。
Cancer Discov. 2014 Sep;4(9):1074-87. doi: 10.1158/2159-8290.CD-14-0353. Epub 2014 Jul 3.
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Fatal neurological side-effects with necrosis of spinal cord following nelarabine treatment in a child with relapsed T-cell acute lymphoblastic leukemia.一名复发的T细胞急性淋巴细胞白血病患儿在接受奈拉滨治疗后出现致命的神经系统副作用并伴有脊髓坏死。
Am J Hematol. 2013 Dec;88(12):1096-7. doi: 10.1002/ajh.23550. Epub 2013 Sep 12.
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Lessons from next-generation sequencing analysis in hematological malignancies.血液恶性肿瘤下一代测序分析的启示。
Blood Cancer J. 2013 Jul 19;3(7):e127. doi: 10.1038/bcj.2013.26.