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卵巢癌的流行病学。

Epidemiology of ovarian cancer.

机构信息

Department of Surgery, Section of Gynecology, National Institute of Medical Sciences and Nutrition "Salvador Zubirán", Mexico City, Mexico.

出版信息

Chin Clin Oncol. 2020 Aug;9(4):47. doi: 10.21037/cco-20-34. Epub 2020 Jun 30.

Abstract

Worldwide, ovarian cancer (OC) is the seventh most common type of malignant neoplasm in women and the eighth cause of mortality in them. The classification of OC is made by the possible origin of one of the three main components of the ovary: epithelium, stroma, and germinal cells. Due to this the main malignant tumors arising from the ovary are epithelial carcinoma, germ cell tumor, sex cord-stromal tumor, and Krukenberg's tumor. The most common are the epithelial carcinomas, in which the most prevalent is serous ovarian carcinoma. Nevertheless, the subtype of OC varies according to the age of appearance. The global incidence of OC has been stable during the last decades, but, it´s still a disease that has contributed to a considerable number of deaths around the world. The epidemiology of this cancer shows differences between races and countries due to several factors including genetic and economic. The detection of this cancer has been problematic as there is no screening public program for its early detection and as a consequence, most OCs are detected in an advanced stage where most of the time it has already spread to other parts different from the ovary. The purpose of this article is to present a comprehensive review of the general epidemiology, incidence rates, prevalence rates, mortality, and survival of the different types of OC worldwide and in certain regions.

摘要

在全球范围内,卵巢癌(OC)是女性中第七种最常见的恶性肿瘤类型,也是导致女性死亡的第八大原因。OC 的分类是根据卵巢的三个主要成分之一的可能起源来进行的:上皮、基质和生殖细胞。因此,主要的恶性肿瘤来自卵巢上皮癌、生殖细胞肿瘤、性索-基质肿瘤和库肯勃瘤。最常见的是上皮癌,其中最常见的是浆液性卵巢癌。然而,OC 的亚型根据出现的年龄而有所不同。在过去几十年中,OC 的全球发病率一直保持稳定,但它仍然是一种导致全球大量死亡的疾病。这种癌症的流行病学因遗传和经济等多种因素在不同种族和国家之间存在差异。由于缺乏针对其早期发现的公共筛查计划,这种癌症的检测一直存在问题,因此大多数 OC 都是在晚期发现的,此时大多数情况下已经扩散到卵巢以外的其他部位。本文的目的是全面综述全球和某些地区不同类型 OC 的一般流行病学、发病率、患病率、死亡率和生存率。

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