Li Gongxin, Wang Feifei, Yang Wenguang, Wang Wenxue, Li Guangyong, Wang Yuechao, Liu Lianqing
State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, China.
Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang, 110016, China.
Adv Biosyst. 2019 Aug;3(8):e1800319. doi: 10.1002/adbi.201800319. Epub 2019 Jun 21.
Biosyncretic systems integrating biological components with electromechanical devices have recently become a promising technology, in which biological components are used as actuators or sensing elements with higher-level performance than artificial systems. Here, a biosyncretic imaging system using an optogenetically engineered living cell as a photodetector is shown. The photoresponsive properties of the cell, such as spectrum and response range, dynamic characteristics, are measured and indicate that the cell functions as an excellent photodetector. In the system, the cell is directly utilized to generate light-triggered ionic currents, which encode the spatial image information and therefore are used to reconstruct the scenes under the view based on compressive sensing. Imaging with the cell-based photodetector is successfully performed by acquiring high-definition images using the system. The system also displays function superiority to a commercial photodiode, such as wider dynamic responsivity range. This work represents a step toward directly imaging with living materials and paves a new road for the development of future on-body bionic devices.
