Ng Janice Natasha C, Wanitphakdeedecha Rungsima, Yan Chadakan
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Cosmet Dermatol. 2020 Sep;19(9):2288-2294. doi: 10.1111/jocd.13613. Epub 2020 Jul 27.
The use of light-emitting diode (LED) in combination wavelength for facial rejuvenation has been previously reported. Nowadays, there has been a growing market for home-use cosmetic devices because of its low cost and convenience.
To evaluate the efficacy and safety of home-use LED device on facial rejuvenation.
This was a prospective split-face clinical trial with a total of 24 subjects, who presented with photo aging skin. All subjects were treated with the home-use LED device on the left side of their face, twice a week for 8 weeks. Primary outcomes measured in the study were the changes in the biophysical properties of the skin assessed with the following parameters: skin elasticity, skin hydration, texture, and wrinkles. Evaluations were done at baseline, 2-, 4-, 6-, and 8-week follow-up. Subjects' self-improvement scores and adverse reactions were also recorded.
All 24 subjects completed the study and attended all follow-up. Skin elasticity was significantly higher in the LED group compared to the control during the 6- and 8-week follow-up (P < .05). In the LED group, an image of the treated skin captured using Visioscan showed improvement of the skin texture at 8-week follow-up. Majority of the subjects in the LED group scored good improvement on all follow-ups (37.5%, 41.7%, 58.3%, and 62.5%) when compared to the baseline. No adverse reactions or pain were recorded in the study.
The home-use LED device, with a combination wavelength of 637 and 854 nm, is safe and can be used as an adjunctive treatment for self-administered facial rejuvenation.
先前已有关于使用组合波长发光二极管（LED）进行面部年轻化治疗的报道。如今，家用美容设备因其低成本和便利性而拥有不断增长的市场。
评估家用LED设备对面部年轻化的疗效和安全性。
这是一项前瞻性半脸临床试验，共有24名呈现光老化皮肤的受试者。所有受试者左侧面部均接受家用LED设备治疗，每周两次，共8周。该研究中测量的主要结果是通过以下参数评估的皮肤生物物理特性的变化：皮肤弹性、皮肤水合作用、质地和皱纹。在基线、随访2周、4周、6周和8周时进行评估。还记录了受试者的自我改善评分和不良反应。
所有24名受试者均完成研究并参加了所有随访。在6周和8周随访期间，LED组的皮肤弹性明显高于对照组（P <.05）。在LED组中，使用Visioscan拍摄的治疗后皮肤图像显示在8周随访时皮肤质地有所改善。与基线相比，LED组的大多数受试者在所有随访中的评分均有良好改善（37.5%、41.7%、58.3%和62.5%）。该研究中未记录到不良反应或疼痛。
波长为637和854 nm的组合波长家用LED设备是安全的，可作为自我面部年轻化的辅助治疗方法。
