Russell B A, Kellett N, Reilly L R
Advanced Laser and Dermatologic Surgery Clinics PC, Beaverton, Oregon 97008, USA.
J Cosmet Laser Ther. 2005 Dec;7(3-4):196-200. doi: 10.1080/14764170500370059.
The use of visible or near infrared spectral light alone for the purpose of skin rejuvenation has been previously reported. A method of light emitting diode (LED) photo rejuvenation incorporating a combination of these wavelengths and thus compounding their distinct stimulation of cellular components is proposed.Objective. To assess the efficacy and local tolerability of combination light therapy in photo rejuvenation of facial skin.
Thirty-one subjects with facial rhytids received nine light therapy treatments using the Omnilux LED system. The treatments combined wavelengths of 633 nm and 830 nm with fluences of 126 J/cm(2) and 66 J/cm(2) respectively. Improvements to the skin surface were evaluated at weeks 9 and 12 by profilometry performed on periorbital casts. Additional outcome measures included assessments of clinical photography and patient satisfaction scores.
Key profilometry results Sq, Sa, Sp and St showed significant differences at week 12 follow-up; 52% of subjects showed a 25%-50% improvement in photoaging scores by week 12; 81% of subjects reported a significant improvement in periorbital wrinkles on completion of follow-up.
Omnilux combination red and near infrared LED therapy represents an effective and acceptable method of photo rejuvenation. Further study to optimize the parameters of treatment is required.
此前已有报道单独使用可见光或近红外光谱光进行皮肤年轻化治疗。本文提出了一种结合这些波长的发光二极管（LED）光嫩肤方法，从而增强其对细胞成分的不同刺激。
评估联合光疗对面部皮肤光嫩肤的疗效和局部耐受性。
31名有面部皱纹的受试者使用Omnilux LED系统接受了9次光疗。治疗结合了633nm和830nm的波长，能量密度分别为126J/cm²和66J/cm²。在第9周和第12周，通过对眶周模型进行轮廓测定来评估皮肤表面的改善情况。其他结果指标包括临床照片评估和患者满意度评分。
关键的轮廓测定结果Sq、Sa、Sp和St在第12周随访时显示出显著差异；到第12周时，52%的受试者光老化评分改善了25%-50%；81%的受试者在随访结束时报告眶周皱纹有显著改善。
Omnilux红和近红外LED联合疗法是一种有效且可接受的光嫩肤方法。需要进一步研究以优化治疗参数。
