Kim Dae Sung, Song Ki Uk, Lee Hae Kwang, Park Jong Ho, Kim Beom Joon, Yoo Kwang Ho, Shin Jin Hee
Research Development Center, CELLRETURN, Incheon, South Korea.
Clinical Research Consultant, Brighlans, Inc., Manila, Philippines.
J Cosmet Dermatol. 2020 Oct;19(10):2606-2615. doi: 10.1111/jocd.13599. Epub 2020 Jul 27.
Recently, light-emitting diode (LED) devices are among those mostly preferred for esthetic application because they improve the appearance of photoaged skin characterized by wrinkles, sagginess, pigmented lesions, and others. In addition, the use of hyaluronic acid (HA) for skin rejuvenation is already well proven.
This study aims to evaluate the synergistic effects of using home-use LED mask device with HA ampoule.
The total number of recruited subjects was 48:24 in Group A treated with both home-use LED mask device and HA ampoule and 24 in Group B treated with HA ampoule only, for 4 weeks. To assess the efficacy of the treatment, the following were used: Antera 3D CS, EOS 800D with Image-Pro Plus, DUB-USB, VisioFace Quick, and Visioscan VC98.
After treatment, the volume measurement (mm ) for prejowl sulci and nasolabial fold flattening as well as the area measurement (pixel) for lower chin firmness improvement was significantly reduced, and the number of pores (ea) for enlarged pores as well as the desquamation index (%) for the amount of corneocytes significantly decreased in both Group A and Group B. Moreover, the percentage of skin density significantly improved. Furthermore, Group A showed a significantly faster and higher rate of improvement than Group B.
The use of 660- and 850-nm home-use LED mask device can generate synergistic effects on home-use topical applications like HA on photoaged face, and such device can be safely and efficiently used daily in personal environments.
最近,发光二极管(LED)设备是美容应用中最受欢迎的设备之一,因为它们可以改善以皱纹、松弛、色素沉着病变等为特征的光老化皮肤的外观。此外,透明质酸(HA)用于皮肤年轻化的效果已得到充分证实。
本研究旨在评估家用LED面罩设备与HA安瓿联合使用的协同效果。
招募的受试者总数为48名:A组24名,同时使用家用LED面罩设备和HA安瓿进行治疗;B组24名,仅使用HA安瓿进行治疗,为期4周。为评估治疗效果,使用了以下设备:Antera 3D CS、配备Image-Pro Plus的EOS 800D、DUB-USB、VisioFace Quick和Visioscan VC98。
治疗后,A组和B组的颌前沟和鼻唇沟变平的体积测量值(mm)以及下巴下部紧致度改善的面积测量值(像素)均显著降低,毛孔扩大的毛孔数量(个)以及角质形成细胞数量的脱屑指数(%)均显著下降。此外,皮肤密度百分比显著提高。此外,A组的改善速度和改善率均显著高于B组。
使用660纳米和850纳米的家用LED面罩设备可以对家用局部应用(如HA)在光老化面部产生协同作用,并且这种设备可以在个人环境中安全有效地日常使用。