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阅读同源:原理、案例研究及其在中国的潜在监管应用。

Read-across: Principle, case study and its potential regulatory application in China.

机构信息

Dow Chemical (China) Investment Company Limited, Beijing, 100738, PR China.

Givaudan Fragrances (Shanghai) Limited, Shanghai, 200123, PR China.

出版信息

Regul Toxicol Pharmacol. 2020 Oct;116:104728. doi: 10.1016/j.yrtph.2020.104728. Epub 2020 Jul 7.

Abstract

Read-across, has generated much attention and has been used in many regulatory schemes as an alternative approach to testing globally. The regulatory application of read-across in the chemical management in China is progressing but still limited. A workshop on the "Read-across: Principle, case study and its potential regulatory application in China", organized by the Chemical Risk Assessment Specialty Group under the Committee of Industrial Toxicology of Chinese Society of Toxicology, was held on May 28, 2019 to discuss the potential broader application and acceptance of read-across to support chemical risk assessment in China. The Workshop included global experts from regulatory agencies, academia and industry. Scientific presentations and constructive discussions raised awareness on the use of read-across in different regions, identified barriers to regulatory acceptance, and participants also brainstormed on practical strategies to help facilitate the further regulatory application of read-across approaches in China.

摘要

-read-across 方法受到广泛关注,并已在许多监管方案中被用作全球测试的替代方法。在中国的化学品管理中,read-across 的监管应用正在取得进展,但仍有限制。中国毒理学会工业毒理专业委员会化学风险评估专业组于 2019 年 5 月 28 日举办了“read-across:原理、案例研究及其在中国的潜在监管应用”研讨会,旨在探讨更广泛地应用和接受 read-across 以支持中国化学品风险评估的潜力。该研讨会邀请了来自监管机构、学术界和行业的全球专家。科学报告和建设性讨论提高了对不同地区使用 read-across 的认识,确定了监管接受的障碍,与会者还集思广益,制定了切实可行的策略,以帮助促进在中国进一步监管应用 read-across 方法。

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