Department of Ophthalmology, University Malaya Medical Centre, Kuala Lumpur, Malaysia; University of Malaya Eye Research Centre (UMERC), Department of Ophthalmology, University of Malaya, Malaysia.
Division of Geriatric Medicine, Department of Medicine, University of Malaya Medical Centre, Kuala Lumpur, Malaysia; Department of Medical Sciences, Faculty of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia.
Arch Gerontol Geriatr. 2020 Sep-Oct;90:104165. doi: 10.1016/j.archger.2020.104165. Epub 2020 Jun 26.
Published literature on vision impairment and cognitive function amongst older Malaysians remains scarce. This study investigates the association between vision impairment and cognitive function in an older Malaysian population.
Subjects aged 55 years and above from the Malaysian Elders Longitudinal Research (MELoR) study with available information on vision and Montreal Cognitive Assessment (MoCA) scores were included. Data were obtained through a home-based interview and hospital-based health check by trained researchers. Visual acuity (VA) was assessed with logMAR score with vision impairment defined as VA 6/18 or worse in the better-seeing eye. Cognition was evaluated using the MoCA-Blind scoring procedure. Those with a MoCA-Blind score of <19/22 were considered to have cognitive impairment.
Data was available for 1144 participants, mean (SD) age = 68.57 (±7.23) years. Vision impairment was present in 143 (12.5 %) and 758 (66.3 %) had MoCA-Blind score of <19. Subjects with vision impairment were less likely to have a MoCA-Blind score of ≥19 (16.8 % vs 36.2 %, p < 0.001). Vision impairment was associated with poorer MoCA-Blind scores after adjustments for age, gender, and ethnicity (β = 2.064; 95 % CI, -1.282 to 3.320; P = 0.003). In those who had > 6 years of education attainment, vision impairment was associated with a significant reduction of cognitive function and remained so after adjustment for age and gender (β = 1.863; 95 % CI, 1.081-3.209; P = 0.025).
Our results suggest that vision impairment correlates with cognitive decline. Therefore, maintaining good vision is an important interventional strategy for preventing cognitive decline in older adults.
发表的关于马来西亚老年人视力障碍和认知功能的文献仍然很少。本研究调查了在马来西亚老年人群体中视力障碍与认知功能之间的关系。
本研究纳入了马来西亚老年人纵向研究（MELoR）中年龄在 55 岁及以上、有视力和蒙特利尔认知评估（MoCA）评分信息的受试者。数据通过经过培训的研究人员进行的家庭访谈和医院健康检查获得。使用 logMAR 分数评估视力敏锐度，将视力 6/18 或更差的较好眼定义为视力障碍。使用 MoCA-Blind 评分程序评估认知能力。MoCA-Blind 评分<19/22 的人被认为存在认知障碍。
共纳入 1144 名参与者，平均（SD）年龄为 68.57（±7.23）岁。143 人（12.5%）存在视力障碍，758 人（66.3%）的 MoCA-Blind 评分<19。视力障碍患者 MoCA-Blind 评分≥19 的可能性较小（16.8%比 36.2%，p<0.001）。在校正年龄、性别和种族后，视力障碍与 MoCA-Blind 评分较差相关（β=2.064；95%置信区间，-1.282 至 3.320；P=0.003）。在受教育程度超过 6 年的人群中，视力障碍与认知功能显著下降相关，在调整年龄和性别后仍然如此（β=1.863；95%置信区间，1.081-3.209；P=0.025）。
我们的结果表明，视力障碍与认知能力下降相关。因此，保持良好的视力是预防老年人认知能力下降的重要干预策略。
