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味觉处理:动物模型的启示。

Taste Processing: Insights from Animal Models.

机构信息

Department of Psychology, Psychobiology Area, University of Huelva, Campus El Carmen, 21071 Huelva, Spain.

Faculty of administrative and social sciences, Autonomous University of Baja California, Tijuana 22890, Mexico.

出版信息

Molecules. 2020 Jul 8;25(14):3112. doi: 10.3390/molecules25143112.

DOI:10.3390/molecules25143112
PMID:32650432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7397205/
Abstract

Taste processing is an adaptive mechanism involving complex physiological, motivational and cognitive processes. Animal models have provided relevant data about the neuroanatomical and neurobiological components of taste processing. From these models, two important domains of taste responses are described in this review. The first part focuses on the neuroanatomical and neurophysiological bases of olfactory and taste processing. The second part describes the biological and behavioral characteristics of taste learning, with an emphasis on conditioned taste aversion as a key process for the survival and health of many species, including humans.

摘要

味觉处理是一种涉及复杂生理、动机和认知过程的适应机制。动物模型为味觉处理的神经解剖学和神经生物学成分提供了相关数据。在这些模型中,本文描述了味觉反应的两个重要领域。第一部分重点介绍嗅觉和味觉处理的神经解剖学和神经生理学基础。第二部分描述了味觉学习的生物学和行为特征,重点介绍条件性味觉厌恶作为许多物种(包括人类)生存和健康的关键过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/7397205/ecd06232e848/molecules-25-03112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/7397205/3dbc892b99bc/molecules-25-03112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/7397205/ecd06232e848/molecules-25-03112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/7397205/3dbc892b99bc/molecules-25-03112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16b9/7397205/ecd06232e848/molecules-25-03112-g002.jpg

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1
Taste Processing: Insights from Animal Models.味觉处理:动物模型的启示。
Molecules. 2020 Jul 8;25(14):3112. doi: 10.3390/molecules25143112.
2
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Inactivation of the basolateral amygdala impairs the retrieval of recent and remote taste-potentiated odor aversion memory.基底外侧杏仁核失活会损害近期和远期味觉增强型气味厌恶记忆的提取。
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Flavor preference learning increases olfactory and gustatory convergence onto single neurons in the basolateral amygdala but not in the insular cortex in rats.味觉偏好学习增加了基底外侧杏仁核中单神经元的嗅觉和味觉汇聚,但在大鼠的岛叶皮质中则没有。
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Reversal learning in larvae.幼虫的反转学习。
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Neuroscience. 2015 Sep 10;303:34-41. doi: 10.1016/j.neuroscience.2015.06.040. Epub 2015 Jun 27.

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本文引用的文献

1
Central taste anatomy and physiology.中枢味觉解剖学与生理学。
Handb Clin Neurol. 2019;164:187-204. doi: 10.1016/B978-0-444-63855-7.00012-5.
2
Activity of Insula to Basolateral Amygdala Projecting Neurons is Necessary and Sufficient for Taste Valence Representation.岛叶投射到基底外侧杏仁核的神经元的活动对于味觉效价的表达是必要且充分的。
J Neurosci. 2019 Nov 20;39(47):9369-9382. doi: 10.1523/JNEUROSCI.0752-19.2019. Epub 2019 Oct 9.
3
Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.识别味道:哺乳动物沿神经轴的编码模式。
Chem Senses. 2019 Apr 15;44(4):237-247. doi: 10.1093/chemse/bjz013.
4
A Pharmacological Perspective on the Study of Taste.味觉研究的药理学视角。
Pharmacol Rev. 2019 Jan;71(1):20-48. doi: 10.1124/pr.118.015974.
5
Flavor recognition memory related activity of the posterior piriform cortex in adult and aged rats.成年和老年大鼠后梨状皮层的味觉识别记忆相关活动。
Behav Brain Res. 2019 Mar 15;360:196-201. doi: 10.1016/j.bbr.2018.12.016. Epub 2018 Dec 7.
6
As Soon as You Taste It: Evidence for Sequential and Parallel Processing of Gustatory Information.一尝便知:味觉信息的顺序和并行处理的证据。
eNeuro. 2018 Oct 23;5(5). doi: 10.1523/ENEURO.0269-18.2018. eCollection 2018 Sep-Oct.
7
A Neural Circuit for Gut-Induced Reward.一条由肠道引发奖赏的神经回路。
Cell. 2018 Oct 18;175(3):887-888. doi: 10.1016/j.cell.2018.10.018.
8
Encoding of Conditioned Taste Aversion in Cortico-Amygdala Circuits.皮质-杏仁核回路中条件性味觉厌恶的编码。
Cell Rep. 2018 Jul 10;24(2):278-283. doi: 10.1016/j.celrep.2018.06.053.
9
Changes in the time of day of conditioning with respect to the pre-exposure interfere with the latent inhibition of conditioned taste aversion in rats.与预暴露相比,条件反射时间的改变会干扰大鼠条件性味觉厌恶的潜伏抑制。
Behav Processes. 2018 Jan;146:22-26. doi: 10.1016/j.beproc.2017.11.003. Epub 2017 Nov 7.
10
Effects of lesions in different nuclei of the amygdala on conditioned taste aversion.杏仁核不同核团损伤对条件性味觉厌恶的影响。
Exp Brain Res. 2017 Nov;235(11):3517-3526. doi: 10.1007/s00221-017-5078-1. Epub 2017 Aug 31.