Department of Environmental and Preventive Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Department of Community Health Sciences, Aga Khan University, Karachi, Sindh, Pakistan.
Rev Environ Health. 2020 Sep 25;35(3):271-275. doi: 10.1515/reveh-2020-0020.
Lead exposure is associated with impaired neurodevelopment among children. House dust is recognized as one of the important secondary sources of lead exposure in children. We assessed the relationship between lead contamination in house dust and blood lead level in Pakistani children. We investigated lead contamination in house dust samples collected from 59 houses in Karachi, Pakistan. The lead content of house dust in Pakistan was relatively higher than that reported in previous studies. Weekly lead intakes from house dust were considerably higher among Pakistani children. In Pakistani children, 12% (7 of 58) showed lead intake values greater than the previous Provisional Tolerable Weekly Intake of lead. A correlation (Pearson's correlation = 0.37) was found between weekly lead intake from house dust and blood lead level in Pakistani children. In addition, blood lead levels were significantly higher in children with high lead intakes than in children with low and medium lead intakes. Thus, house dust is an important source of lead exposure in Pakistani children.
铅暴露与儿童神经发育受损有关。房屋灰尘被认为是儿童铅暴露的重要次要来源之一。我们评估了巴基斯坦儿童房屋灰尘中铅污染与血铅水平之间的关系。我们调查了从巴基斯坦卡拉奇的 59 所房屋中收集的房屋灰尘样本中的铅污染情况。巴基斯坦房屋灰尘中的铅含量高于以往研究报告的含量。巴基斯坦儿童从房屋灰尘中摄入的铅每周都相当高。在巴基斯坦儿童中，有 12%（58 名中的 7 名）显示出铅摄入量超过之前暂定每周耐受摄入量的铅。在巴基斯坦儿童中，从房屋灰尘中摄入的每周铅量与血铅水平之间存在相关性（皮尔逊相关系数=0.37）。此外，高铅摄入量儿童的血铅水平明显高于低和中铅摄入量儿童。因此，房屋灰尘是巴基斯坦儿童铅暴露的重要来源。
