Roberts John W, Wallace Lance A, Camann David E, Dickey Philip, Gilbert Steven G, Lewis Robert G, Takaro Tim K
US Environmental Protection Agency, Reston, VA 22091, USA.
Rev Environ Contam Toxicol. 2009;201:1-39. doi: 10.1007/978-1-4419-0032-6_1.
The health risks to babies from pollutants in house dust may be 100 times greater than for adults. The young ingest more dust and are up to ten times more vulnerable to such exposures. House dust is the main exposure source for infants to allergens, lead, and PBDEs, as well as a major source of exposure to pesticides, PAHs, Gram-negative bacteria, arsenic, cadmium, chromium, phthalates, phenols, and other EDCs, mutagens, and carcinogens. Median or upper percentile concentrations in house dust of lead and several pesticides and PAHs may exceed health-based standards in North America. Early contact with pollutants among the very young is associated with higher rates of chronic illness such as asthma, loss of intelligence, ADHD, and cancer in children and adults. The potential of infants, who live in areas with soil contaminated by automotive and industrial emissions, can be given more protection by improved home cleaning and hand washing. Babies who live in houses built before 1978 have a prospective need for protection against lead exposures; homes built before 1940 have even higher lead exposure risks. The concentration of pollutants in house dust may be 2-32 times higher than that found in the soil near a house. Reducing infant exposures, at this critical time in their development, may reduce lifetime health costs, improve early learning, and increase adult productivity. Some interventions show a very rapid payback. Two large studies provide evidence that home visits to reduce the exposure of children with poorly controlled asthma triggers may return more than 100% on investment in 1 yr in reduced health costs. The tools provided to families during home visits, designed to reduce dust exposures, included vacuum cleaners with dirt finders and HEPA filtration, allergy control bedding covers, high-quality door mats, and HEPA air filters. Infants receive their highest exposure to pollutants in dust at home, where they spend the most time, and where the family has the most mitigation control. Normal vacuum cleaning allows deep dust to build up in carpets where it can be brought to the surface and become airborne as a result of activity on the carpet. Vacuums with dirt finders allow families to use the three-spot test to monitor deep dust, which can reinforce good cleaning habits. Motivated families that receive home visits from trained outreach workers can monitor and reduce dust exposures by 90% or more in 1 wk. The cost of such visits is low considering the reduction of risks achieved. Improved home cleaning is one of the first results observed among families who receive home visits from MHEs and CHWs. We believe that proven intervention methods can reduce the exposure of infants to pollutants in house dust, while recognizing that much remains to be learned about improving the effectiveness of such methods.
家庭灰尘中的污染物对婴儿造成的健康风险可能比对成年人高100倍。幼儿吸入的灰尘更多,对这类接触的易感性高达成年人的十倍。家庭灰尘是婴儿接触过敏原、铅和多溴二苯醚的主要来源,也是接触杀虫剂、多环芳烃、革兰氏阴性菌、砷、镉、铬、邻苯二甲酸盐、酚类及其他内分泌干扰物、诱变剂和致癌物的主要来源。在北美,家庭灰尘中铅以及几种杀虫剂和多环芳烃的中位浓度或较高百分位数浓度可能超过基于健康的标准。幼儿早期接触污染物与儿童和成人中较高的慢性病发病率相关,如哮喘、智力丧失、注意力缺陷多动障碍和癌症。生活在汽车和工业排放污染土壤地区的婴儿,通过改善家庭清洁和洗手可以得到更多保护。居住在1978年以前建造房屋中的婴儿可能需要预防铅暴露;1940年以前建造的房屋铅暴露风险甚至更高。家庭灰尘中的污染物浓度可能比房屋附近土壤中的污染物浓度高2至32倍。在婴儿发育的这个关键时期减少其接触污染物,可能会降低一生的健康成本、改善早期学习并提高成年后的生产力。一些干预措施显示出非常快的投资回报。两项大型研究表明,家访以减少哮喘触发因素控制不佳的儿童的接触,在一年中可使健康成本降低,投资回报率超过100%。家访期间提供给家庭的旨在减少灰尘接触的工具包括带有灰尘探测器和高效空气过滤器的吸尘器、过敏控制床罩、高质量门垫和高效空气过滤器。婴儿在家中接触灰尘中污染物的机会最多,因为他们在家中度过的时间最长,而且家庭在这方面有最大的缓解控制能力。普通的真空清洁会使深层灰尘积聚在地毯中,在地毯上的活动会使这些灰尘带到表面并扬起。带有灰尘探测器的吸尘器使家庭能够使用三点测试来监测深层灰尘,这可以强化良好的清洁习惯。接受训练有素的外展工作人员家访的积极家庭,在一周内可以将灰尘接触量监测并减少90%或更多。考虑到所实现的风险降低,这种家访的成本很低。改善家庭清洁是接受母婴健康专家和社区卫生工作者家访的家庭中最早观察到的结果之一。我们相信,经过验证的干预方法可以减少婴儿接触家庭灰尘中的污染物,同时认识到在提高这些方法有效性方面仍有许多需要学习的地方。