复方新诺明所致急性肉芽肿性间质性肾炎
Acute granulomatous interstitial nephritis due to co-trimoxazole.
作者信息
Cryst C, Hammar S P
机构信息
Virginia Mason Clinic, Seattle, Wash.
出版信息
Am J Nephrol. 1988;8(6):483-8. doi: 10.1159/000167666.
PMID:3265285
Abstract
A 51-year-old man with diabetes mellitus and mild hypertension developed acute interstitial nephritis 4 days after starting a course of co-trimoxazole for bronchopneumonia. Following initial symptoms of overt hypersensitivity, he developed azotemia and renal tubular dysfunction with malaise and anorexia requiring hospitalization. Renal pathology demonstrated an acute granulomatous interstitial nephritis superimposed on chronic diabetic renal disease.
摘要
一名51岁患有糖尿病和轻度高血压的男性，在开始使用复方新诺明治疗支气管肺炎4天后发生了急性间质性肾炎。在出现明显过敏的初始症状后，他出现了氮质血症和肾小管功能障碍，并伴有全身不适和食欲不振，需要住院治疗。肾脏病理学显示为急性肉芽肿性间质性肾炎叠加在慢性糖尿病肾病之上。
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