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由可可链霉菌引起的慢性化脓性中耳炎,为人类感染的第二例报告。

Chronic suppurative otitis media due to Streptomyces cacaoi, the second case report in human infection.

机构信息

Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, Guangdong, China.

出版信息

BMC Infect Dis. 2020 Jul 11;20(1):499. doi: 10.1186/s12879-020-05222-0.

DOI:10.1186/s12879-020-05222-0
PMID:32652948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7353713/
Abstract

BACKGROUND

Streptomyces cacaoi, Gram-positive, branched, filamentous bacillus forms without fragmentation, are saprophytic soil organisms rarely known to cause invasive infections other than mycetoma. Here we describe a case of chronic suppurative otitis media caused by Streptomyces cacaoi in a patient with hyperlipidemia in China.

CASE PRESENTATION

A 62-year-old female patient with hyperlipidemia suffered chronic suppurative otitis media caused by Streptomyces cacaoi. She had a favorable outcome with a 4-week course of ofloxacin ear drops.

CONCLUSIONS

Streptomyces cacaoi is rarely reported to cause human infection. The introduction of molecular techniques improves the ability to identify rare species such as Streptomyces considerably. We report the case improve our ability to identify this pathogen and expand the range of known bacterial causes of human infection.

摘要

背景

可可链霉菌是革兰氏阳性、分枝、丝状杆菌,不分裂,是腐生土壤生物,除足菌肿外,很少引起侵袭性感染。在此,我们描述了一例中国高血脂患者由可可链霉菌引起的慢性化脓性中耳炎。

病例介绍

一名 62 岁的女性高血脂患者患有可可链霉菌引起的慢性化脓性中耳炎。她使用氧氟沙星滴耳液 4 周后,结果良好。

结论

可可链霉菌很少引起人类感染。分子技术的引入极大地提高了识别稀有物种(如链霉菌)的能力。我们报告该病例,以提高我们识别这种病原体的能力,并扩大已知可引起人类感染的细菌范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/06f849f1ab44/12879_2020_5222_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/9a2b87128cb8/12879_2020_5222_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/598814f16360/12879_2020_5222_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/06f849f1ab44/12879_2020_5222_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/9a2b87128cb8/12879_2020_5222_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/598814f16360/12879_2020_5222_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51e4/7353713/06f849f1ab44/12879_2020_5222_Fig3_HTML.jpg

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