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腹腔内骨外骨肉瘤:病例报告及文献复习。

Intraperitoneal extraosseous osteosarcoma: a case report and literatures review.

机构信息

Departments of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.

Research Centre for Regenerative Medicine, Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, 22 Shuangyong Road, Nanning, Guangxi, China.

出版信息

BMC Musculoskelet Disord. 2020 Jul 11;21(1):452. doi: 10.1186/s12891-020-03429-5.

DOI:10.1186/s12891-020-03429-5
PMID:32653041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7353749/
Abstract

BACKGROUND

To investigate the clinical imaging manifestations, diagnosis and treatment of intraperitoneal extraosseous osteosarcoma.

CASE PRESENTATION

A 52-year-old male patient with intraperitoneal extraosseous osteosarcoma was retrospectively analyzed. He suffered from left lower abdominal pain accompanied by mass for 6 months. On abdominal CT scan, multiple patchy and banded calcification were found. The largest is about six centimeters in diameter and underwent mass resection. Postoperative pathology revealed retroperitoneal osteosarcoma. The reported intraperitoneal extraosseous osteosarcoma was analyzed and the related literature was reviewed. Two years after operation, the patients had recurrence of the tumors and invaded sigmoid colon, peritoneum and bladder. Palliative operation was performed to remove the tumors in the bladder and transverse colostomy was performed. The patients were followed up by telephone and died 2 months after the second operation.

CONCLUSIONS

Intraperitoneal extraosseous osteosarcoma has a low incidence and has no specific imaging features. Surgical resection is the main treatment and the prognosis is poor.

摘要

背景

探讨腹腔外骨外骨肉瘤的临床影像学表现、诊断和治疗。

病例介绍

回顾性分析 1 例腹腔外骨外骨肉瘤患者,男,52 岁,左下腹疼痛伴包块 6 个月。腹部 CT 扫描发现多处斑片状和条带状钙化,最大直径约 6cm,行肿块切除术。术后病理提示为腹膜后骨肉瘤。报道了腹腔外骨外骨肉瘤,并复习了相关文献。术后 2 年,患者肿瘤复发并侵犯乙状结肠、腹膜和膀胱。行姑息性手术切除膀胱肿瘤,并横结肠造口术。通过电话进行随访,患者在第二次手术后 2 个月死亡。

结论

腹腔外骨外骨肉瘤发病率低,影像学特征无特异性。手术切除是主要治疗方法,预后差。

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Prognostic implication of adjuvant/neoadjuvant chemotherapy consisting of doxorubicin and ifosfamide in patients with extraskeletal osteosarcoma.阿霉素和异环磷酰胺辅助/新辅助化疗对骨外骨肉瘤患者的预后意义。
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