Department of Pediatrics, Section of Cardiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Department of Pediatrics, Section of Cardiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Can J Cardiol. 2020 Sep;36(9):1344-1351. doi: 10.1016/j.cjca.2020.07.002. Epub 2020 Jul 10.
Cardiovascular disease remains the leading cause of death worldwide. Although there is little direct evidence that ties the presence of risk factors in childhood with adult cardiovascular disease, there are multiple indirect lines of evidence that, when synthesized, make a strong case for maintaining cardiovascular health through childhood and adolescence as well as screening for and treating risk factors when they develop to diminish lifetime risk. This review summarizes these lines of evidence and asserts that it is imperative that primordial and primary cardiovascular risk reduction begins early.
心血管疾病仍然是全球范围内的主要死因。虽然没有直接证据表明儿童时期存在的危险因素与成人心血管疾病有关，但有多种间接证据表明，将这些证据综合起来，可以强有力地证明通过儿童期和青春期保持心血管健康以及在危险因素出现时进行筛查和治疗以降低终生风险的重要性。这篇综述总结了这些证据，并断言， primordial 和 primary 心血管风险降低必须尽早开始。
