Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany,
Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health (CIMH), Heidelberg University, Medical Faculty Mannheim, Mannheim, Germany,
Eur Addict Res. 2020;26(4-5):245-253. doi: 10.1159/000508918. Epub 2020 Jul 10.
Alcohol dependence (AD) is frequently associated with attention-deficit/hyperactivity disorder (ADHD) as well as with posttraumatic stress disorder (PTSD).
Aim of this study was to investigate whether in patients with AD, ADHD is associated with an increased rate of exposure to potentially traumatic events (PTEs) and PTSD, with increased PTSD severity and higher impact on daily functioning.
Patients with AD were thoroughly assessed for ADHD during long-term residential treatment. Participants also completed the Posttraumatic Diagnostic Scale (PDS). The PDS is a 49-item self-report instrument that assesses exposure to different PTEs, DSM-IV criteria for PTSD, severity of PTSD, and related functional impairment.
Of 341 patients with AD, 66 were diagnosed with ADHD (19%). ADHD was associated with a more frequent exposure to PTEs (88 vs. 65%, p < 0.001). In patients with PTEs (n = 237), odds for PTSD were higher in ADHD versus no-ADHD patients (OR 8.9, 95% CI 3.9-20.5). Furthermore, PTSD severity and functional impairment were increased in ADHD patients.
ADHD in patients with AD is associated with a higher frequency of PTEs and PTSD with more severe and more impairing PTSD symptoms. In alcohol-dependent patients with ADHD, regular screening for PTSD should be considered.
酒精依赖(AD)常与注意缺陷多动障碍(ADHD)以及创伤后应激障碍(PTSD)有关。
本研究旨在探讨 AD 患者中 ADHD 是否与更高的创伤后应激障碍(PTSD)发生率、更高的 PTSD 严重程度和对日常生活功能的更大影响有关。
在长期住院治疗期间,对 AD 患者进行 ADHD 全面评估。参与者还完成了创伤后诊断量表(PDS)。PDS 是一个 49 项的自我报告工具,评估了不同创伤后应激源的暴露、DSM-IV 创伤后应激障碍标准、PTSD 严重程度以及相关的功能障碍。
在 341 名 AD 患者中,有 66 名被诊断为 ADHD(19%)。ADHD 与更频繁的创伤后应激源暴露有关(88%比 65%,p < 0.001)。在有创伤后应激源暴露的患者中(n = 237),ADHD 患者发生 PTSD 的几率高于无 ADHD 患者(OR 8.9,95% CI 3.9-20.5)。此外,ADHD 患者的 PTSD 严重程度和功能障碍都增加了。
AD 患者中的 ADHD 与创伤后应激源的发生频率更高以及 PTSD 有关,其 PTSD 症状更严重且对日常生活功能的影响更大。对于有 ADHD 的酒精依赖患者,应定期筛查 PTSD。