Luderer Mathias, Seidt Johanna, Gerhardt Sarah, Hoffmann Sabine, Vollstädt-Klein Sabine, Reif Andreas, Sobanski Esther
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Front Psychiatry. 2023 Mar 6;14:1112843. doi: 10.3389/fpsyt.2023.1112843. eCollection 2023.
Attention deficit/hyperactivity disorder (ADHD) is common in alcohol use disorder (AUD). Continuous performance tests (CPTs) allow to measure ADHD related deficits in a laboratory setting. Most studies on this topic focused on CPTs measuring inattention or impulsivity, disregarding hyperactivity as one of the core symptoms of ADHD.
We examined = 47 in three groups (ADHD = 19; AUD = 16; ADHD + AUD = 12) with questionnaires on ADHD core symptoms, executive functioning (EF), mind wandering, and quality of life (QoL). = 46 (ADHD = 16; AUD = 16; ADHD + AUD = 14) were examined with a CPT (QbTest) that also measures motor activity objectively.
Inattention and impulsivity were significantly increased in AUD vs. ADHD and in AUD vs. ADHD + AUD. Hyperactivity was significantly higher in ADHD + AUD vs. ADHD and ADHD + AUD vs. AUD, but not in ADHD vs. AUD. EF was lower in both ADHD groups vs. AUD. Mind wandering was increased in both ADHD groups vs. AUD. QoL was significantly lower in ADHD + AUD compared to AUD. In contrast, results of the QbTest were not significantly different between groups.
Questionnaires are more useful in assessing ADHD core symptoms than the QbTest. Hyperactivity appears to be a relevant symptom in ADHD + AUD, suggesting a possible pathway from ADHD to AUD. The lower QoL in ADHD + AUD emphasizes the need for routine screening, diagnostic procedures and treatment strategies for this patient group.
注意力缺陷多动障碍(ADHD)在酒精使用障碍(AUD)中很常见。持续操作测试(CPT)能够在实验室环境中测量与ADHD相关的缺陷。关于这个主题的大多数研究都集中在测量注意力不集中或冲动性的CPT上,而忽视了多动是ADHD的核心症状之一。
我们对三组共47名受试者(ADHD组19名;AUD组16名;ADHD+AUD组12名)进行了问卷调查,内容涉及ADHD核心症状、执行功能(EF)、走神和生活质量(QoL)。对46名受试者(ADHD组16名;AUD组16名;ADHD+AUD组14名)进行了CPT(QbTest)测试,该测试也能客观测量运动活动。
与ADHD组相比以及与ADHD+AUD组相比,AUD组的注意力不集中和冲动性显著增加。与ADHD组相比以及与AUD组相比,ADHD+AUD组的多动显著更高,但ADHD组与AUD组相比多动无显著差异。与AUD组相比,两个ADHD组的EF较低。与AUD组相比,两个ADHD组的走神增加。与AUD组相比,ADHD+AUD组的QoL显著更低。相比之下,各组之间QbTest的结果无显著差异。
在评估ADHD核心症状方面,问卷调查比QbTest更有用。多动似乎是ADHD+AUD中的一个相关症状,提示了一条从ADHD到AUD的可能途径。ADHD+AUD组较低的QoL强调了对该患者群体进行常规筛查、诊断程序和治疗策略的必要性。