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古线粒体基因组揭示中国南方与东南亚大陆之间的旧石器时代遗传联系。

Paleolithic genetic link between Southern China and Mainland Southeast Asia revealed by ancient mitochondrial genomes.

机构信息

Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, Institute of Vertebrate Paleontology and Paleoanthropology, CAS, 100044, Beijing, China.

Center for Excellence in Life and Paleoenvironment, Chinese Academy of Sciences, 100044, Beijing, China.

出版信息

J Hum Genet. 2020 Dec;65(12):1125-1128. doi: 10.1038/s10038-020-0796-9. Epub 2020 Jul 11.

DOI:10.1038/s10038-020-0796-9
PMID:32653893
Abstract

The genetic history of Southern East Asians is not well-known, especially prior to the Neolithic period. To address this, we successfully sequenced two complete mitochondrial genomes of 11,000-year-old human individuals from Southern China, thus generating the oldest ancient DNA sequences from this area. Integrating published mitochondrial genomes, we characterized M71d, a new subhaplogroup of haplogroup M71. Our results suggest a possible early migration between Southern China and mainland Southeast Asia by at least 22,000 BP.

摘要

东亚南部人群的遗传历史并不为人所知,尤其是在新石器时代之前。为了解决这一问题,我们成功地对来自中国南部的两个 11000 年前的人类个体进行了全基因组测序,从而获得了该地区最古老的古 DNA 序列。整合已发表的线粒体基因组数据,我们鉴定了 M71d,这是 M71 单倍群下的一个新的亚单倍群。我们的研究结果表明,早在 22000 年前,东亚南部人群和东南亚大陆之间可能就已经存在早期的迁徙。

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