Tanner A R, Robinson D P
Department of Medicine, North Tees General Hospital, Stockton on Tees, Cleveland.
Gut. 1988 Dec;29(12):1736-40. doi: 10.1136/gut.29.12.1736.
A comparison between the NBT-PABA/14C-PABA test (NBT-PABA, n-benzoyl-tyrosyl para-aminobenzoic acid) using the PABA excretion index (PEI) and serum PABA estimation at 90 minutes has been made in 42 consecutive subjects attending for investigation of possible pancreatic disease to a District General Hospital (DGH). The PEI was unobtainable or incorrect on 38% of occasions compared with 9% for the serum test. Sensitivity, specificity, and efficiency for the PEI (n = 33 valid results) were 71%, 88%, and 79% respectively and for the serum PABA (n = 41 valid results), 95%, 90%, and 93% respectively. These results confirm that measurement of serum PABA is a simpler, more reliable, and a more accurate method of assessing pancreatic function.
在一家地区综合医院（DGH），对42名因可能患有胰腺疾病前来就诊的连续患者进行了一项比较，该比较采用对氨基苯甲酸排泄指数（PEI）的对硝基苯甲酰-对氨基苯甲酸/¹⁴C-对氨基苯甲酸试验（NBT-PABA，正苯甲酰-酪氨酰对氨基苯甲酸），并在90分钟时测定血清对氨基苯甲酸。与血清检测9%的情况相比，PEI在38%的情况下无法获得或结果不正确。PEI（n = 33个有效结果）的敏感性、特异性和效率分别为71%、88%和79%，血清对氨基苯甲酸（n = 41个有效结果）的敏感性、特异性和效率分别为95%、90%和93%。这些结果证实，测定血清对氨基苯甲酸是一种更简单、更可靠且更准确的评估胰腺功能的方法。
