关于胰腺功能的BT对氨基苯甲酸/14C-对氨基苯甲酸无管试验的观察

Observations on the BT PABA/14C-PABA tubeless test of pancreatic function.

作者信息

Braganza J M, Kay G H, Tetlow V A, Herman K J

出版信息

Clin Chim Acta. 1983 Jun 15;130(3):339-47. doi: 10.1016/0009-8981(83)90308-x.

Abstract

The diagnostic accuracy of the BT PABA/14C-PABA tubeless test of pancreatic function was assessed in a prospective study of 140 patients. Drug or isotopic interference invalidated 16 tests (11.4%). The sensitivity of the PABA/14C excretion index was 76.7% and the specificity 85.7% using the mean -2 SD value of 0.82 as the cut-off point; 74.4% sensitivity and 95.7% specificity using the mean -3 SD value of 0.76. The potential usefulness and limitations of this modern version of the PABA test are discussed.

摘要

在一项针对140例患者的前瞻性研究中，评估了BT PABA/14C - PABA无管胰腺功能试验的诊断准确性。药物或同位素干扰使16项试验无效（11.4%）。以0.82的均值 - 2标准差作为截断点时，PABA/14C排泄指数的敏感性为76.7%，特异性为85.7%；以0.76的均值 - 3标准差作为截断点时，敏感性为74.4%，特异性为95.7%。讨论了这种现代版PABA试验的潜在用途和局限性。