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卵巢小细胞癌伴嗜钙性（SCCOHT）：新诊断的年轻成人的综合管理。

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Comprehensive management of a newly diagnosed young adult.

机构信息

Department of Pediatrics, University of Cincinnati College of Medicine, United States of America; Division of Oncology, Cincinnati Children's Hospital Medical Center, United States of America.

Department of Pediatrics, University of Cincinnati College of Medicine, United States of America; Division of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, United States of America.

出版信息

Gynecol Oncol. 2020 Sep;158(3):538-546. doi: 10.1016/j.ygyno.2020.06.160. Epub 2020 Jul 10.

DOI:10.1016/j.ygyno.2020.06.160
PMID:32654763
Abstract

SCCOHT is an aggressive malignancy linked to alterations of SMARCA4. We describe the diagnosis and therapy of a 32 year old who received multi-agent chemotherapy and underwent a second look operation with HIPEC followed by high-dose chemotherapy with stem cell transplant. Supportive care, oncofertility, and genetic counseling are described.

摘要

SCCOHT 是一种侵袭性恶性肿瘤，与 SMARCA4 改变有关。我们描述了一位 32 岁患者的诊断和治疗过程，该患者接受了多药物化疗，并进行了第二次手术，术中进行 HIPEC 及高剂量化疗联合干细胞移植。还描述了支持性治疗、肿瘤生育力保留和遗传咨询。

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