非酒精性脂肪性肝病：临床与病理相关性综述。
Non-alcoholic fatty liver disease: A review with clinical and pathological correlation.
机构信息
Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Department of Pathology, University of Washington School of Medicine, Seattle, United States; Department of Medicine, University of Washington School of Medicine, Seattle, United States.
出版信息
J Formos Med Assoc. 2021 Jan;120(1 Pt 1):68-77. doi: 10.1016/j.jfma.2020.07.006. Epub 2020 Jul 9.
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in North America and Europe, with increasing prevalence in other regions of the world. Its spectrum encompass steatosis, non-alcoholic steatohepatitis (NASH), fibrosis and cirrhosis. It is considered as the manifestation of metabolic syndrome in liver, and its development and progression is influenced by complex interaction of environmental and genetic factors. In this review we discuss the histopathological features, differential diagnoses, and the commonly used grading and staging systems of NAFLD. NAFLD associated with other diseases, histological changes after therapeutic intervention and recurrence or occurrence of NAFLD after liver transplantation are also addressed.
非酒精性脂肪性肝病（NAFLD）是北美和欧洲最常见的慢性肝病，在世界其他地区的患病率也在不断增加。其谱包括脂肪变性、非酒精性脂肪性肝炎（NASH）、纤维化和肝硬化。它被认为是代谢综合征在肝脏中的表现，其发生和发展受到环境和遗传因素的复杂相互作用的影响。在这篇综述中，我们讨论了 NAFLD 的组织病理学特征、鉴别诊断以及常用的分级和分期系统。还讨论了与其他疾病相关的 NAFLD、治疗干预后的组织学变化以及肝移植后 NAFLD 的复发或发生。
Zotero 插件