对鼻腔、咽喉和鼻咽部进行耐甲氧西林筛查：一项试点研究。
Screening the nose, throat and the naso-pharynx for methicillin-resistant : a pilot study.
作者信息
Uwemedimo Joy, Fitzgerald-Hughes Deirdre, Kinnevey Peter, Shore Anna, Coleman David, Humphreys Hilary, Poovelikunnel Toney Thomas
机构信息
Dublin Institute of Technology, Dublin, Ireland.
Department of Clinical Microbiology, Royal College of Surgeons in Ireland, ERC, Dublin, Ireland.
出版信息
J Infect Prev. 2020 Jul;21(4):155-158. doi: 10.1177/1757177420921915. Epub 2020 Jun 13.
Abstract
Patients who carry nasal methicillin-resistant (MRSA) may also harbour MRSA in the oro-pharyngeal cavity. However, the naso-oro-pharyngeal co-carriage is infrequently assessed. The incidence of concurrent MRSA carriage of the naso-oro-pharynx was ascertained, and the sensitivity of two methods, a throat swab and a phosphate buffered saline (PBS) oral rinse, for MRSA detection was investigated. Among nasal MRSA carriers, 80% harboured MRSA in the oro-pharynx. Among these patients, 15% had MRSA detected in the oro-pharynx and not in the throat. Oro-pharyngeal colonisation represents a significant reservoir to persistence as well as nasal recolonisation. Decolonisation methods effective in reducing oro-pharyngeal MRSA in addition to nasal carriage should be investigated.
摘要
携带耐甲氧西林金黄色葡萄球菌（MRSA）的患者，其口咽腔也可能存在MRSA。然而，鼻-口咽共同携带情况很少得到评估。本研究确定了鼻-口咽同时携带MRSA的发生率，并研究了两种检测MRSA方法（咽拭子和磷酸盐缓冲盐水（PBS）口腔冲洗）的敏感性。在鼻MRSA携带者中，80%的患者口咽部存在MRSA。在这些患者中，15%的患者口咽部检测到MRSA，而咽喉部未检测到。口咽部定植是持续感染以及鼻腔重新定植的重要储存库。除鼻腔携带外，还应研究有效减少口咽部MRSA的去定植方法。
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