Rao Preetham, Bhide Priya
Homerton University Hospital NHS Foundation Trust, London, UK.
Homerton Fertility Centre, Homerton University Hospital NHS Foundation Trust, London E9 6SR, UK.
Ther Adv Reprod Health. 2020 Jun 29;14:2633494120913032. doi: 10.1177/2633494120913032. eCollection 2020 Jan-Dec.
Polycystic ovary syndrome is a common endocrinological condition which is found to be prevalent in 5-10% of women of reproductive age. Historically, a combination of anovulation and androgen excess was considered a hallmark in the diagnosis of polycystic ovary syndrome. Addition of ultrasound features of polycystic ovary syndrome has improved the detection of variation in the polycystic ovary syndrome phenotype. Despite the widespread use of consensus diagnostic criteria, there remain several unresolved controversies in the diagnosis of polycystic ovary syndrome. Difficulty arises in methods of assessment and types of androgens to be measured to detect biochemical hyperandrogenism, setting a cut-off value for the diagnosis of clinical hyperandrogenism, setting an ultrasound threshold of antral follicle count to diagnose polycystic ovaries and also diagnosing this condition in adolescence where there is no clear definition for 'irregular cycles'. This article looks at various controversies in the diagnosis of polycystic ovary syndrome.
多囊卵巢综合征是一种常见的内分泌疾病，在5%-10%的育龄女性中较为普遍。从历史上看，无排卵和雄激素过多的组合被认为是多囊卵巢综合征诊断的标志。多囊卵巢综合征超声特征的加入提高了对多囊卵巢综合征表型变异的检测。尽管广泛使用了共识诊断标准，但在多囊卵巢综合征的诊断中仍存在一些未解决的争议。在评估方法和检测生化高雄激素血症时要测量的雄激素类型、设定临床高雄激素血症诊断的临界值、设定诊断多囊卵巢的窦卵泡计数超声阈值以及在青春期诊断这种疾病（因为青春期对于“月经周期不规律”没有明确的定义）方面都存在困难。本文探讨了多囊卵巢综合征诊断中的各种争议。
