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多囊卵巢综合征的地域流行率因地区和种族/民族而异。

Geographical Prevalence of Polycystic Ovary Syndrome as Determined by Region and Race/Ethnicity.

机构信息

Physician Assistant and Registered Dietitian at Apex Family Medicine, Denver, CO 80209, USA.

Department of Human Nutrition and Foods, West Virginia University, Morgantown, WV 26506, USA.

出版信息

Int J Environ Res Public Health. 2018 Nov 20;15(11):2589. doi: 10.3390/ijerph15112589.

DOI:10.3390/ijerph15112589
PMID:30463276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6266413/
Abstract

Polycystic ovarian syndrome (PCOS) is thought to be the most common endocrine disorder found in women. Common symptoms include irregular menstrual cycle, polycystic ovaries, and hirsutism, as well as an increased risk for a multitude of conditions, including insulin resistance, dyslipidemia and infertility. The prevalence of polycystic ovarian syndrome is generally thought to be between 3% and 10% but it is widely unknown for specific subpopulations based on geographical location and race/ethnicity. Based on the high degree of variability and inconsistencies between the different diagnostic criteria, there is a unique challenge that exists when determining the prevalence of this syndrome. There are a large percentage of individuals that remain undiagnosed even after visiting multiple health care providers. Most studies conducted across the world are limited by small sample size, selection bias, and lack of comparability across studies. There have been very few studies that have examined the prevalence of polycystic ovary syndrome across the United States. Based on the National Institutes of Health (NIH)'s diagnostic criteria, there is a similar prevalence of PCOS documented across the United States, the United Kingdom, Spain, Greece, Australia, and Mexico. Other studies have shown some differences between geographical location and race. The existing data is not conclusive enough to determine whether or not there is any significant differences in the prevalence of PCOS across geographical location, racial or ethnic groups. This review will seek to determine the prevalence of polycystic ovarian syndrome based on geographical location and race/ethnicity.

摘要

多囊卵巢综合征(PCOS)被认为是女性最常见的内分泌疾病。常见症状包括月经周期不规律、多囊卵巢和多毛症,以及多种疾病的风险增加,包括胰岛素抵抗、血脂异常和不孕。多囊卵巢综合征的患病率一般认为在 3%到 10%之间,但由于地理位置和种族/民族的不同,具体亚群的患病率尚不清楚。由于不同诊断标准之间存在高度的可变性和不一致性,因此在确定该综合征的患病率时存在独特的挑战。即使就诊于多个医疗机构,仍有很大一部分人未被诊断出来。世界上大多数研究受到样本量小、选择偏差和研究之间缺乏可比性的限制。很少有研究在美国检查多囊卵巢综合征的患病率。根据美国国立卫生研究院(NIH)的诊断标准,美国、英国、西班牙、希腊、澳大利亚和墨西哥都有类似的多囊卵巢综合征患病率。其他研究表明,地理位置和种族之间存在一些差异。现有数据还不够确定,无法确定地理位置、种族或民族之间多囊卵巢综合征的患病率是否存在任何显著差异。本综述将旨在根据地理位置和种族/民族确定多囊卵巢综合征的患病率。

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