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节菱孢菌素E-G，来自植物内生真菌节菱孢菌HS66的三种波卓烷倍半萜类化合物。

Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66.

作者信息

Su Xiao-Zheng, Tang Jian-Wei, Hu Kun, Li Xiao-Nian, Sun Han-Dong, Puno Pema-Tenzin

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.

出版信息

Nat Prod Bioprospect. 2020 Aug;10(4):201-207. doi: 10.1007/s13659-020-00248-y. Epub 2020 Jul 12.

DOI:10.1007/s13659-020-00248-y
PMID:32656629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7367987/
Abstract

Arthrinins E-G (1-3), three new sesquiterpenoids possessing non-isoprenoid botryane skeleton, were isolated from the fermentation of an endophytic fungus named Arthrinium sp. HS66 which colonized in the stems of Isodon xerophilus. Their structures were determined by extensive spectroscopic methods. Furthermore, the structure of 1 was unambiguously confirmed by X-ray diffraction, while those of 2 and 3 were verified through quantum chemical calculation of NMR data and ECD spectra.

摘要

从定殖于干旱香茶菜茎中的内生真菌链格孢属真菌HS66的发酵产物中分离得到了三种具有非异戊二烯基葡萄藻烷骨架的新倍半萜——节菱孢菌素E-G（1-3）。通过广泛的光谱方法确定了它们的结构。此外，通过X射线衍射明确证实了1的结构，而2和3的结构则通过对核磁共振数据和电子圆二色光谱的量子化学计算得到了验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/450c70255e74/13659_2020_248_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/9209a5752e26/13659_2020_248_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/15d38cceb4e7/13659_2020_248_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/c0f541080427/13659_2020_248_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/2de9fa2227d8/13659_2020_248_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/450c70255e74/13659_2020_248_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/9209a5752e26/13659_2020_248_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/15d38cceb4e7/13659_2020_248_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/c0f541080427/13659_2020_248_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/2de9fa2227d8/13659_2020_248_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb5c/7367987/450c70255e74/13659_2020_248_Fig5_HTML.jpg

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