Sección Serología y Pruebas Diagnósticas, Instituto de Zoonosis Luis Pasteur, Ciudad Autónoma de Buenos Aires, Argentina.
División de Acciones Comunitarias para la Salud, Instituto de Zoonosis Luis Pasteur, Ciudad Autónoma de Buenos Aires, Argentina.
Comp Immunol Microbiol Infect Dis. 2020 Oct;72:101515. doi: 10.1016/j.cimid.2020.101515. Epub 2020 Jun 30.
At least 15 of the 30 Bartonella species are involved in human pathologies, and several of them are associated with rodents and their fleas. The aims of this study were detect and molecularly characterize the Bartonella infections in rodents from an urban protected area of Buenos Aires City (Argentina). A total of 186 rodents were captured and identified. For PCR of the 16S rRNA fragment, 23.7 % of the samples tested positive, and two groups (GrA and GrB) were identified. Likewise, the comparison between the sequences obtained for the gltA gene determined the presence of three genotypes, closely related to Bartonella spp. detected in sigmodontine rodents and their fleas in the Americas, which form a well-separated clade. The high prevalence of Bartonella in rodents from an urban protected area of Buenos Aires city is relevant from a public health perspective.
至少有 30 种巴尔通体物种中的 15 种与人类病理学有关，其中有几种与啮齿动物及其跳蚤有关。本研究的目的是检测和分子特征分析布宜诺斯艾利斯市一个城市保护区的啮齿动物中的巴尔通体感染。共捕获并鉴定了 186 只啮齿动物。对 16S rRNA 片段进行 PCR 检测，有 23.7%的样本呈阳性，确定了两个组（GrA 和 GrB）。同样，对 gltA 基因获得的序列进行比较，确定了三种基因型的存在，这些基因型与在美洲的沙鼠及其跳蚤中检测到的巴尔通体属密切相关，它们形成了一个很好分开的分支。布宜诺斯艾利斯市城市保护区的啮齿动物中巴尔通体的高流行率从公共卫生的角度来看是相关的。
