Moiseev S I
Kardiologiia. 1988 Nov;28(11):67-71.
Patients with angina of effort, both its stable and progressive variants, show hypercoagulative hemostatic shifts and a deterioration of blood rheologic properties, the changes being more pronounced in progressive angina. Vascular-wall changes, dependent on the level of plasma Willebrand's factor, are closely related to clinical severity of angina of effort. The latter is also related to changes in blood rheology (increased erythrocyte aggregation, reduced erythrocyte deformation and high platelet adhesion).
劳力性心绞痛患者,包括稳定型和进行性变异型,均表现出高凝性止血变化以及血液流变学特性的恶化,这些变化在进行性心绞痛中更为明显。取决于血浆血管性血友病因子水平的血管壁变化,与劳力性心绞痛的临床严重程度密切相关。后者还与血液流变学的变化有关(红细胞聚集增加、红细胞变形能力降低以及血小板高黏附性)。