Altern Ther Health Med. 2021 Jun;27(S1):46-53.
Even though positive treatment outcomes for type 2 diabetes mellitus (T2DM) are linked to disease knowledge and adherence to medications, inadequate knowledge, poor adherence, and resistance to lifestyle modifications are still common among patients. This situation has been a continuing dilemma for patients and healthcare providers, and these factors negatively affect the health-related quality of life (HRQoL) of patients.
The current study intended to evaluate the correlations between diabetes-related knowledge, medication adherence, and HRQoL among T2DM patients in Pakistan.
The study was designed as a questionnaire-based, cross-sectional descriptive analysis, with participants being selected using a prevalence-based sampling method.
The study was conducted at four different healthcare institutes namely Sandeman Provincial Hospital, Bolan Medical Complex Hospital, Al-Khair Hospital and Sajid Hospital, Quetta city, Pakistan.
Participants were 300 patients with T2DM who were receiving treatment at public and private healthcare institutes in Quetta, Pakistan.
In addition to collection of demographics, the Urdu version of Michigan Diabetes Knowledge Test (MDKT-U), the Drug Attitude Inventory (DAI-10), and the EuroQol EQ-5D were used to assess diabetes-related knowledge, medication adherence and HRQoL, respectively. The relationships among the 3 variables were determined using the Spearmen rho correlation coefficient, and the results were interpreted using Cohen' criteria. SPSS v.20 was used for data analysis, and P < .05 was considered significant for all analysis.
The mean diabetes-related knowledge score was 5.83 ± 1.92, indicating participants' lack of knowledge of T2DM. Moderate adherence was reported, with a mean adherence score of 4.94 ± 2.72. Additionally, the mean EQ-5D score was 0.48±0.36, and the mean Visual Analogue Score (VAS) was 54.58 ± 20.28, highlighting poor HRQoL. The Spearman's rho correlation coefficient indicated significant, moderate correlations among all variables (P < .05; r = 0.053-0.231).
The study found limited diabetes-related knowledge, moderate medication adherence, and poor HRQoL among patients with T2DM in Pakistan. Nevertheless, a positive significant correlation revealed that a directly proportional change in one study variable can improve the others.
尽管 2 型糖尿病（T2DM）的积极治疗结果与疾病知识和药物依从性有关，但患者中仍然普遍存在知识不足、药物依从性差以及对生活方式改变的抵制。这种情况一直是患者和医疗保健提供者的持续困境，这些因素对患者的健康相关生活质量（HRQoL）产生负面影响。
本研究旨在评估巴基斯坦 T2DM 患者的糖尿病相关知识、药物依从性与 HRQoL 之间的相关性。
本研究设计为基于问卷调查的横断面描述性分析，采用基于患病率的抽样方法选择参与者。
本研究在巴基斯坦奎达市的四家不同的医疗保健机构进行，包括桑德曼省级医院、博兰医疗综合医院、阿尔凯医院和赛义德医院。
参与者为 300 名在巴基斯坦奎达的公立和私立医疗机构接受治疗的 T2DM 患者。
除了收集人口统计学数据外，还使用了密歇根糖尿病知识测试（MDKT-U）的乌尔都语版本、药物态度量表（DAI-10）和 EuroQol EQ-5D 来评估糖尿病相关知识、药物依从性和 HRQoL。使用斯皮尔曼 rho 相关系数确定 3 个变量之间的关系，并使用科恩标准解释结果。使用 SPSS v.20 进行数据分析，所有分析均以 P <.05 为显著。
糖尿病相关知识得分的平均值为 5.83 ± 1.92，表明参与者对 T2DM 的知识不足。报告的药物依从性为中度，平均依从性评分为 4.94 ± 2.72。此外，平均 EQ-5D 得分为 0.48±0.36，平均视觉模拟评分（VAS）为 54.58 ± 20.28，表明 HRQoL 较差。斯皮尔曼 rho 相关系数表明所有变量之间存在显著的中度相关性（P <.05；r = 0.053-0.231）。
本研究发现巴基斯坦 T2DM 患者的糖尿病相关知识有限、药物依从性中度和 HRQoL 较差。然而，正相关表明研究变量的直接比例变化可以改善其他变量。
