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亲水型种植体表面对骨整合的影响:兔的生物力学研究结果

Impact of a Hydrophilic Dental Implant Surface on Osseointegration: Biomechanical Results in Rabbit.

机构信息

Department of Oral and Maxillofacial Surgery and Oral Medicine, Faculty of Odontology, Malmö University, Malmö, Sweden.

Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.

出版信息

J Oral Implantol. 2021 Apr 1;47(2):163-168. doi: 10.1563/aaid-joi-D-19-00217.

DOI:10.1563/aaid-joi-D-19-00217
PMID:32663272
Abstract

This study aimed to evaluate the effect of surface hydrophilicity on the biomechanical aspects of osseointegration of dental implants in the tibia and femur of rabbits. Forty-eight mature female New Zealand White rabbits were included, and 96 commercially pure, Grade 4, titanium dental implants (control group), and 96 implants of same macro geometry with the hydrophilic surface (test group) were used in this study. One osteotomy was performed in each tibia and femur on both sides of the rabbit, and four implants were placed in each rabbit. Control and test groups were randomly allocated on the left and right sides. During surgery, insertion torque (ITQ) value of the complete implant placement was recorded. After healing periods of 0, 2, 4, and 8 weeks after surgery, implant stability quotient (ISQ) value, and removal torque (RTQ) values were measured. No statistical difference was observed for ITQ, for ISQ and for RTQ between the control group and test group in tibia/femur for all time periods. The effect of hydrophilic properties on moderately roughened surfaces has no impact in terms of biomechanical outcomes (ISQ values and RTQ values) after a healing period of 2 to 8 weeks in rabbit tibias /femurs.

摘要

本研究旨在评估表面亲水性对兔胫骨和股骨中牙种植体骨整合的生物力学方面的影响。纳入 48 只成熟雌性新西兰白兔,使用 96 枚商用纯 4 级钛牙科种植体(对照组)和 96 枚具有亲水表面的同种宏观几何形状的种植体(实验组)。在兔子的每侧胫骨和股骨上进行一次截骨,每只兔子放置 4 枚种植体。对照组和实验组随机分配在左侧和右侧。在手术过程中,记录完整种植体放置的插入扭矩(ITQ)值。在手术后 0、2、4 和 8 周的愈合期后,测量种植体稳定性指数(ISQ)值和去除扭矩(RTQ)值。在胫骨/股骨的所有时间段,对照组和实验组之间的 ITQ、ISQ 和 RTQ 均无统计学差异。在兔胫骨/股骨 2 至 8 周的愈合期后,亲水性能对中度粗糙表面的生物力学结果(ISQ 值和 RTQ 值)没有影响。

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